Spontaneous myelofibrosis in castrated and ovariectomized NMRI mice

The histopathological appearance of myelofibrosis of the bone marrow is described in aged castrated males, ovariectomized females and in male and female control NMRI mice. The highest incidence of the lesion was observed in ovariectomized and female control mice where more than 90% of the animals we...

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Veröffentlicht in:	Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1997-12, Vol.49 (5), p.351-353
Hauptverfasser:	Rittinghausen, S., Kohler, M., Kamino, K., Dasenbrock, C., Mohr, U.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Biological and medical sciences Bone Marrow - pathology Bone marrow, myelofibrosis Castration - veterinary Female Gonadal hormones, myelofibrosis Hematologic and hematopoietic diseases Incidence Male Medical sciences Mice Mice, Inbred Strains Myelofibrosis Other diseases. Hematologic involvement in other diseases Ovariectomy - veterinary Primary Myelofibrosis - epidemiology Primary Myelofibrosis - pathology Primary Myelofibrosis - veterinary Rodent Diseases - epidemiology Rodent Diseases - pathology Sex Factors
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