Recombinant, truncated CD4 molecule (rT4) binds IgG

CD4 is a cell surface glycoprotein that identifies the subset of human T lymphocytes that induces sIg+ B lymphocytes to differentiate and secrete Ig after intimate T-B cell contact. In the course of studying a recombinant, truncated form of CD4 (rT4) we noticed that goat antibodies of apparently irr...

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Veröffentlicht in:	The Journal of immunology (1950) 1990-01, Vol.144 (1), p.214-220
Hauptverfasser:	Lederman, S, Yellin, MJ, Cleary, AM, Gulick, R, Chess, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - immunology Binding Sites CD4 Antigens - metabolism Humans Hydrogen-Ion Concentration Immunoglobulin Fc Fragments - metabolism Immunoglobulin G - metabolism In Vitro Techniques Peptide Fragments - metabolism Recombinant Proteins - metabolism Solubility Structure-Activity Relationship
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