Afterload reduction with vasodilators and diuretics decreases mitral regurgitation during upright exercise in advanced heart failure

In advanced heart failure, mitral regurgitation increases the burden of the failing ventricle and decreases effective stroke volume. Although tailored afterload reduction decreases mitral regurgitation at rest, it is not known if this benefit is maintained during upright exercise. Simultaneous radio...

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Veröffentlicht in:	Journal of the American College of Cardiology 1990-01, Vol.15 (1), p.174-180
Hauptverfasser:	Stevenson, Lynne Warner, Brunken, Richard C., Belil, Dalila, Grover-McKay, Maleah, Schwaiger, Markus, Schelbert, Heinrich R., Tillisch, Jan H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antianginal agents. Coronary vasodilator agents Biological and medical sciences Bumetanide - therapeutic use Cardiovascular system Diuretics - therapeutic use Exercise - physiology Female Ferricyanides - therapeutic use Furosemide - therapeutic use Heart - diagnostic imaging Heart Failure - drug therapy Heart Failure - physiopathology Humans Male Medical sciences Middle Aged Mitral Valve Insufficiency - drug therapy Mitral Valve Insufficiency - physiopathology Nitroprusside - therapeutic use Pharmacology. Drug treatments Pulmonary Wedge Pressure - drug effects Radionuclide Imaging Stroke Volume - drug effects Thermodilution Vascular Resistance - drug effects
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