Effect of age and gender on the pharmacokinetics of grepafloxacin

The effects of age and gender on the pharmacokinetics of the oral fluoroquinolone grepafloxacin were examined in 48 healthy middle-aged and elderly individuals, of whom half were male and half were female. Participants were stratified into 4 groups (each with n = 12), aged 40 to 49 years, 50 to 59 y...

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Veröffentlicht in:	Clinical pharmacokinetics 1997, Vol.33 Suppl 1 (Supplement 1), p.9-17
Hauptverfasser:	Efthymiopoulos, C, Bramer, S L, Maroli, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Age Factors Aged Anti-Infective Agents - administration & dosage Anti-Infective Agents - blood Anti-Infective Agents - pharmacokinetics Area Under Curve Female Fluoroquinolones Half-Life Humans Male Middle Aged Piperazines - administration & dosage Piperazines - blood Piperazines - pharmacokinetics Quinolones - administration & dosage Quinolones - blood Quinolones - pharmacokinetics Sex Factors
Online-Zugang:	Volltext
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