Effect of Delayed Intervention with ACE-inhibitor Therapy on Myocyte Hypertrophy and Growth of the Cardiac Interstitium in the Rat Model of Myocardial Infarction

The effectiveness of angiotensin-converting enzyme (ACE)-inhibitor therapy in attenuating ventricular remodeling when initiated immediately following myocardial damage is clearly established. Less information, however, is available on the impact of late therapy on the remodeling process, especially...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 1997-12, Vol.29 (12), p.3203-3210
Hauptverfasser:	McDonald, Kenneth M., Chu, Cuixia, Francis, Gary S., Carlyle, Wenda, Judd, Dianne L., Hauer, Katherine, Hartman, Malinda, Cohn, Jay N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin converting enzyme inhibitor Angiotensin-Converting Enzyme Inhibitors - administration & dosage Angiotensin-Converting Enzyme Inhibitors - therapeutic use Animals Captopril - therapeutic use Cardiomegaly - pathology Collagen - analysis Disease Models, Animal Drug Administration Schedule Endothelium, Vascular - pathology Mycocyte hypertrophy Myocardial Infarction - drug therapy Myocardial Infarction - pathology Myocardium - pathology Rat myocardial infarction Rats Rats, Sprague-Dawley Renin - blood Ventricular remodeling
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