Preclinical Pharmacology of Zofenopril, an Inhibitor of Angiotensin I Converting Enzyme

Zofenopril calcium (one-half calcium salt) is a prodrug ester analog of captopril whose biological effects are manifested by its active component, SQ 26,333. Because of the relative insolubilities of both zofenopril calcium and SQ 26,333, zofenopril potassium salt and SQ 26,703, the arginine salt of...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1989-06, Vol.13 (6), p.887-894
Hauptverfasser:	DeForrest, J M, Waldron, T L, Krapcho, J, Turk, C, Rubin, B, Powell, J R, Cushman, D W, Petrillo, E W
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - metabolism Animals Antihypertensive agents Biological and medical sciences Biological Availability Blood Pressure - drug effects Captopril - analogs & derivatives Captopril - pharmacokinetics Captopril - pharmacology Cardiovascular system Dogs Female Ileum In Vitro Techniques Macaca fascicularis Male Medical sciences Muscle Contraction - drug effects Pharmacology. Drug treatments Rats
Online-Zugang:	Volltext
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