Immunohistochemical detection of human milk components aspirated in lungs of an infant
We examined an autopsy case of an infant whose cause of death was suspected to be asphyxia due to human breast milk aspiration. In order to demonstrate aspirated milk in the lungs, we conducted immunohistochemical staining using eight antibodies against the components of human milk. Seven of the eig...
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| Veröffentlicht in: | Forensic science international 1997-11, Vol.90 (1), p.77-84 |
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| container_title | Forensic science international |
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| creator | Iwadate, K Sakamoto, N Park, S.H Doy, M Iwase, H Nagao, M Takatori, T |
| description | We examined an autopsy case of an infant whose cause of death was suspected to be asphyxia due to human breast milk aspiration. In order to demonstrate aspirated milk in the lungs, we conducted immunohistochemical staining using eight antibodies against the components of human milk. Seven of the eight antibodies reacted positively with the substances suspected to be aspirated milk. We concluded that immunohistochemical staining with these antibodies is useful to demonstrate human milk aspiration and provide some keys for detecting the causes of unexpected infant deaths. |
| doi_str_mv | 10.1016/S0379-0738(97)00152-7 |
| format | Article |
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In order to demonstrate aspirated milk in the lungs, we conducted immunohistochemical staining using eight antibodies against the components of human milk. Seven of the eight antibodies reacted positively with the substances suspected to be aspirated milk. We concluded that immunohistochemical staining with these antibodies is useful to demonstrate human milk aspiration and provide some keys for detecting the causes of unexpected infant deaths.</description><identifier>ISSN: 0379-0738</identifier><identifier>EISSN: 1872-6283</identifier><identifier>DOI: 10.1016/S0379-0738(97)00152-7</identifier><identifier>PMID: 9438367</identifier><identifier>CODEN: FSINDR</identifier><language>eng</language><publisher>Kidlington: Elsevier Ireland Ltd</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Antibodies ; Antigens ; Asphyxia ; Aspiration ; Autopsies ; Autopsy ; Autopsy - methods ; Babies ; Biological and medical sciences ; Breast cancer ; Breast milk ; Breastfeeding & lactation ; Cardiopulmonary resuscitation ; Cause of Death ; CPR ; Emergency and intensive care: neonates and children. Prematurity. Sudden death ; Esophagus ; Gastroesophageal Reflux - complications ; Humans ; Immunohistochemistry ; Immunology ; Infant mortality ; Infant, Newborn ; Infants ; Intensive care medicine ; Lung - pathology ; Lungs ; Male ; Medical sciences ; Milk ; Milk, Human - chemistry ; Morphology ; Oils & fats ; Pneumonia ; Pneumonia, Aspiration - etiology ; Pneumonia, Aspiration - pathology ; Proteins ; Staining ; Sudden infant death</subject><ispartof>Forensic science international, 1997-11, Vol.90 (1), p.77-84</ispartof><rights>1997 Elsevier Science Ireland Ltd</rights><rights>1998 INIST-CNRS</rights><rights>1997. 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In order to demonstrate aspirated milk in the lungs, we conducted immunohistochemical staining using eight antibodies against the components of human milk. Seven of the eight antibodies reacted positively with the substances suspected to be aspirated milk. We concluded that immunohistochemical staining with these antibodies is useful to demonstrate human milk aspiration and provide some keys for detecting the causes of unexpected infant deaths.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Antibodies</subject><subject>Antigens</subject><subject>Asphyxia</subject><subject>Aspiration</subject><subject>Autopsies</subject><subject>Autopsy</subject><subject>Autopsy - methods</subject><subject>Babies</subject><subject>Biological and medical sciences</subject><subject>Breast cancer</subject><subject>Breast milk</subject><subject>Breastfeeding & lactation</subject><subject>Cardiopulmonary resuscitation</subject><subject>Cause of Death</subject><subject>CPR</subject><subject>Emergency and intensive care: neonates and children. Prematurity. Sudden death</subject><subject>Esophagus</subject><subject>Gastroesophageal Reflux - complications</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Immunology</subject><subject>Infant mortality</subject><subject>Infant, Newborn</subject><subject>Infants</subject><subject>Intensive care medicine</subject><subject>Lung - pathology</subject><subject>Lungs</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Milk</subject><subject>Milk, Human - chemistry</subject><subject>Morphology</subject><subject>Oils & fats</subject><subject>Pneumonia</subject><subject>Pneumonia, Aspiration - etiology</subject><subject>Pneumonia, Aspiration - pathology</subject><subject>Proteins</subject><subject>Staining</subject><subject>Sudden infant death</subject><issn>0379-0738</issn><issn>1872-6283</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkUuLFDEURoMoY8_oTxgoUGRclOZRqSSrQQYfAwMufGxDkrqxM1aSNqkS_Pemp5teuHF1F9_5LpdzEbok-A3BZHz7BTOheiyYvFLiNcaE0148QhsiBe1HKtljtDkhT9F5rfcYY87peIbO1MAkG8UGfb-NcU15G-qS3RZicGbuJljALSGnLvtuu0aTuhjmn53LcZcTpKV2pu5CMQtMXUjdvKYfdc82MCRv0vIMPfFmrvD8OC_Qtw_vv9586u8-f7y9eXfXu4GIpScwUks8DE4wbqx0DI9cWswZoZa1TFnPqB-NBevBcyqlEYSpwQPmbrLsAr067N2V_GuFuugYqoN5NgnyWrVQnFLBhga--Ae8z2tJ7TZNVZOHiWKiUfxAuZJrLeD1roRoyh9NsN5b1w_W9V6pVkI_WNf73uVx-2ojTKfWUXPLXx5zU5tgX0xyoZ4wipWSGDfs-oBBU_Y7QNHVBUgOplDaQ_SUw38O-QtED56h</recordid><startdate>19971110</startdate><enddate>19971110</enddate><creator>Iwadate, K</creator><creator>Sakamoto, N</creator><creator>Park, S.H</creator><creator>Doy, M</creator><creator>Iwase, H</creator><creator>Nagao, M</creator><creator>Takatori, T</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>19971110</creationdate><title>Immunohistochemical detection of human milk components aspirated in lungs of an infant</title><author>Iwadate, K ; Sakamoto, N ; Park, S.H ; Doy, M ; Iwase, H ; Nagao, M ; Takatori, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c417t-1e62b1fe4c735ab8c30658b05312b362b9bf32f6abebfef5288a71394fe05cdb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Antibodies</topic><topic>Antigens</topic><topic>Asphyxia</topic><topic>Aspiration</topic><topic>Autopsies</topic><topic>Autopsy</topic><topic>Autopsy - methods</topic><topic>Babies</topic><topic>Biological and medical sciences</topic><topic>Breast cancer</topic><topic>Breast milk</topic><topic>Breastfeeding & lactation</topic><topic>Cardiopulmonary resuscitation</topic><topic>Cause of Death</topic><topic>CPR</topic><topic>Emergency and intensive care: neonates and children. Prematurity. Sudden death</topic><topic>Esophagus</topic><topic>Gastroesophageal Reflux - complications</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Immunology</topic><topic>Infant mortality</topic><topic>Infant, Newborn</topic><topic>Infants</topic><topic>Intensive care medicine</topic><topic>Lung - pathology</topic><topic>Lungs</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Milk</topic><topic>Milk, Human - chemistry</topic><topic>Morphology</topic><topic>Oils & fats</topic><topic>Pneumonia</topic><topic>Pneumonia, Aspiration - etiology</topic><topic>Pneumonia, Aspiration - pathology</topic><topic>Proteins</topic><topic>Staining</topic><topic>Sudden infant death</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Iwadate, K</creatorcontrib><creatorcontrib>Sakamoto, N</creatorcontrib><creatorcontrib>Park, S.H</creatorcontrib><creatorcontrib>Doy, M</creatorcontrib><creatorcontrib>Iwase, H</creatorcontrib><creatorcontrib>Nagao, M</creatorcontrib><creatorcontrib>Takatori, T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Forensic science international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Iwadate, K</au><au>Sakamoto, N</au><au>Park, S.H</au><au>Doy, M</au><au>Iwase, H</au><au>Nagao, M</au><au>Takatori, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Immunohistochemical detection of human milk components aspirated in lungs of an infant</atitle><jtitle>Forensic science international</jtitle><addtitle>Forensic Sci Int</addtitle><date>1997-11-10</date><risdate>1997</risdate><volume>90</volume><issue>1</issue><spage>77</spage><epage>84</epage><pages>77-84</pages><issn>0379-0738</issn><eissn>1872-6283</eissn><coden>FSINDR</coden><abstract>We examined an autopsy case of an infant whose cause of death was suspected to be asphyxia due to human breast milk aspiration. In order to demonstrate aspirated milk in the lungs, we conducted immunohistochemical staining using eight antibodies against the components of human milk. Seven of the eight antibodies reacted positively with the substances suspected to be aspirated milk. We concluded that immunohistochemical staining with these antibodies is useful to demonstrate human milk aspiration and provide some keys for detecting the causes of unexpected infant deaths.</abstract><cop>Kidlington</cop><pub>Elsevier Ireland Ltd</pub><pmid>9438367</pmid><doi>10.1016/S0379-0738(97)00152-7</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0379-0738 |
| ispartof | Forensic science international, 1997-11, Vol.90 (1), p.77-84 |
| issn | 0379-0738 1872-6283 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antibodies Antigens Asphyxia Aspiration Autopsies Autopsy Autopsy - methods Babies Biological and medical sciences Breast cancer Breast milk Breastfeeding & lactation Cardiopulmonary resuscitation Cause of Death CPR Emergency and intensive care: neonates and children. Prematurity. Sudden death Esophagus Gastroesophageal Reflux - complications Humans Immunohistochemistry Immunology Infant mortality Infant, Newborn Infants Intensive care medicine Lung - pathology Lungs Male Medical sciences Milk Milk, Human - chemistry Morphology Oils & fats Pneumonia Pneumonia, Aspiration - etiology Pneumonia, Aspiration - pathology Proteins Staining Sudden infant death |
| title | Immunohistochemical detection of human milk components aspirated in lungs of an infant |
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