Structure and Serotonin 5-HT2C Receptor Activity of ortho- and meta-Substituted Phenylpiperazines

The structural characteristics of ortho- and meta-substituted phenylpiperazines have been investigated in order to understand their actions at the serotonin 5-HT2C receptor. The crystal structures of the 4-methylated analogues of two phenylpiperazines that are already known as 5-HT2C ligands, 1-(1-n...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Acta crystallographica. Section B, Structural science Structural science, 1997-12, Vol.53 (6), p.976-983
Hauptverfasser:	Verdonk, M. L., Voogd, J. W., Kanters, J. A., Kroon, J., Den Besten, R., Brandsma, L., Leysen, D., Kelder, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Condensed matter: structure, mechanical and thermal properties Exact sciences and technology Heterocyclic compounds Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Organic compounds Pharmacology. Drug treatments Physics Piperazines - chemistry Piperazines - pharmacology Receptor, Serotonin, 5-HT2C Receptors, Serotonin - drug effects Serotonin Receptor Agonists - chemistry Serotonin Receptor Agonists - pharmacology Serotoninergic system Structure of solids and liquids crystallography Structure of specific crystalline solids Structure-Activity Relationship Thermodynamics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!