Stage T1c prostate cancer: defining the appropriate staging evaluation and the role for pelvic lymphadenectomy
A good staging system should be able to accurately reflect the natural history of a malignant disease, to express the extent of the disease at the time of diagnosis, and stratify patients in prognostically distinctive groups. The staging system for prostate cancer, as it is today, fails to fulfill t...
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Veröffentlicht in: | World journal of urology 1997-11, Vol.15 (6), p.346-358 |
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creator | Beduschi, M C Beduschi, R Oesterling, J E |
description | A good staging system should be able to accurately reflect the natural history of a malignant disease, to express the extent of the disease at the time of diagnosis, and stratify patients in prognostically distinctive groups. The staging system for prostate cancer, as it is today, fails to fulfill these requirements. Approximately one third of the patients who undergo surgery for complete excision of prostate cancer in fact do not have a localize disease. The incidence of tumor at the inked margin may reach 30% for T1 stage and up to 60% for clinical T2b prostate cancer according to comparison with pathologic examination of resected specimen. Several concepts have been recently proposed as a means of improving the accuracy of the available staging system. In this paper, we review current aspects of clinical and pathological staging of prostate cancer, and the importance of these new concepts on the early stages of prostate cancer. |
doi_str_mv | 10.1007/BF01300182 |
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The staging system for prostate cancer, as it is today, fails to fulfill these requirements. Approximately one third of the patients who undergo surgery for complete excision of prostate cancer in fact do not have a localize disease. The incidence of tumor at the inked margin may reach 30% for T1 stage and up to 60% for clinical T2b prostate cancer according to comparison with pathologic examination of resected specimen. Several concepts have been recently proposed as a means of improving the accuracy of the available staging system. In this paper, we review current aspects of clinical and pathological staging of prostate cancer, and the importance of these new concepts on the early stages of prostate cancer.</description><identifier>ISSN: 0724-4983</identifier><identifier>EISSN: 1433-8726</identifier><identifier>DOI: 10.1007/BF01300182</identifier><identifier>PMID: 9436284</identifier><language>eng</language><publisher>Germany: Springer Nature B.V</publisher><subject>Humans ; Lymph Node Excision ; Male ; Medical research ; Neoplasm Staging ; Pelvis - surgery ; Prostate cancer ; Prostatic Neoplasms - pathology ; Prostatic Neoplasms - surgery ; Time Factors</subject><ispartof>World journal of urology, 1997-11, Vol.15 (6), p.346-358</ispartof><rights>Springer-Verlag 1997</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c237t-15faacdf5536738e24052a6cbf8e79780014002584c183d58292c9b10e65d6603</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9436284$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Beduschi, M C</creatorcontrib><creatorcontrib>Beduschi, R</creatorcontrib><creatorcontrib>Oesterling, J E</creatorcontrib><title>Stage T1c prostate cancer: defining the appropriate staging evaluation and the role for pelvic lymphadenectomy</title><title>World journal of urology</title><addtitle>World J Urol</addtitle><description>A good staging system should be able to accurately reflect the natural history of a malignant disease, to express the extent of the disease at the time of diagnosis, and stratify patients in prognostically distinctive groups. 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subjects | Humans Lymph Node Excision Male Medical research Neoplasm Staging Pelvis - surgery Prostate cancer Prostatic Neoplasms - pathology Prostatic Neoplasms - surgery Time Factors |
title | Stage T1c prostate cancer: defining the appropriate staging evaluation and the role for pelvic lymphadenectomy |
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