Secretion of functional Renilla reniformis luciferase by mammalian cells

The soft coral Renilla reniformis luciferase enzyme is a monomeric soluble intracellular protein that is used increasingly as a marker of gene expression. Here the Renilla luciferase gene was engineered to encode a protein product secreted by mammalian cells. The 5′ end of the Renilla luciferase gen...

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