Oral platinum analogue JM216, a radiosensitizer in oxic murine cells

This study was designed to compare radiosensitization by the oral platinum compound JM216 with cisplatin. RIF1 mouse tumour cells were treated at various doses and at various exposure times with JM216 and irradiated 15 min before the end of drug exposure. The fraction of cells surviving treatment wa...

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Veröffentlicht in:	International journal of radiation biology 1997, Vol.72 (6), p.675-683
Hauptverfasser:	VAN DE VAART, P. J. M, KLAREN, H. M, HOFLAND, I, BEGG, A. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Biological and medical sciences Biological effects of radiation Cisplatin - pharmacology DNA Adducts - analysis Fundamental and applied biological sciences. Psychology Mice Organoplatinum Compounds - metabolism Organoplatinum Compounds - pharmacology Radiation-Sensitizing Agents - pharmacology Radiosensitizing agents. Photosensitizing agents. Thermosensitizing agents Space life sciences Tissues, organs and organisms biophysics Tumor Cells, Cultured
Online-Zugang:	Volltext
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