Cloning and in situ hybridization analysis of the expression of polysialyltransferase mRNA in the developing and adult rat brain

Polysialyltransferase (PST) is an enzyme that catalyzes the addition of polysialic acid (PSA), a homopolymer of α-2,8-linked sialic acid residues, onto neural cell adhesion molecule (NCAM). The expression of PSA-NCAM in the brain is developmentally regulated and is of critical importance; however, t...

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Veröffentlicht in:	Brain research. Molecular brain research. 1997-11, Vol.51 (1), p.69-81
Hauptverfasser:	Wood, Graham K, Liang, Jin-Jun, Flores, Gonzalo, Ahmad, Sultan, Quirion, Remi, Srivastava, Lalit K
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Amino Acid Sequence Animals Biological and medical sciences Brain Brain - embryology Brain - enzymology Brain - growth & development Cloning, Molecular - methods Cricetinae Development Development. Senescence. Regeneration. Transplantation Embryonic and Fetal Development Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental Gene Expression Regulation, Enzymologic Gestational Age Humans Hybridization, in situ In Situ Hybridization Male Mice Molecular Sequence Data mRNA Polysialyltransferase Pregnancy PSA-NCAM Rat Rats Rats, Sprague-Dawley Recombinant Proteins - biosynthesis Recombinant Proteins - chemistry RNA, Messenger - biosynthesis Sequence Alignment Sequence Homology, Amino Acid Sialyltransferases - biosynthesis Sialyltransferases - chemistry Transcription, Genetic Vertebrates: nervous system and sense organs
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