Effect of selenium, vitamin E and riboflavin supplementation of the feed on the humoral and cell-mediated immune responses of growing pigs
The feed of weaned piglets of Hungarian Large White X Duroc genotype was supplemented with 0.5 mg selenium, 50, 100 or 150 mg vitamin E, and 2.5 or 5 mg riboflavin per kg. Feed supplementation enhanced the cytotoxic reaction and elevated the antibody titres produced against purified horse gamma glob...
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Veröffentlicht in: | Acta veterinaria Hungarica (Budapest. 1983) 1989, Vol.37 (3), p.201-217 |
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container_title | Acta veterinaria Hungarica (Budapest. 1983) |
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creator | Rafai, P Tuboly, S Jakab, L Papp, Z Molnar, L. (University of Veterinary Sciences, Budapest (Hungary)) Biro, H. (KA-HYB Pig Breeding and Marketing Co., Kaposvar (Hungary)) |
description | The feed of weaned piglets of Hungarian Large White X Duroc genotype was supplemented with 0.5 mg selenium, 50, 100 or 150 mg vitamin E, and 2.5 or 5 mg riboflavin per kg. Feed supplementation enhanced the cytotoxic reaction and elevated the antibody titres produced against purified horse gamma globulin antigen. However, as compared to the control the differences were not significant. Feed supplementation exerted a beneficial, though varying, influence on the indices of cell-mediated immunity. The proportion of rosette-forming cells and blastogenic transformation induced by specific (horse globulin) and nonspecific (phytohaemagglutinin, PHA) mitogens underwent the most expressed and most significant increase in pigs fed 5 mg selenium, 100 mg vitamin E and 5 mg rivoflavin per kg of feed. On the other hand, feed supplementation failed to enhance the responsiveness to intradermal PHA (type IV allergic reaction). |
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(University of Veterinary Sciences, Budapest (Hungary)) ; Biro, H. (KA-HYB Pig Breeding and Marketing Co., Kaposvar (Hungary))</creator><creatorcontrib>Rafai, P ; Tuboly, S ; Jakab, L ; Papp, Z ; Molnar, L. (University of Veterinary Sciences, Budapest (Hungary)) ; Biro, H. (KA-HYB Pig Breeding and Marketing Co., Kaposvar (Hungary))</creatorcontrib><description>The feed of weaned piglets of Hungarian Large White X Duroc genotype was supplemented with 0.5 mg selenium, 50, 100 or 150 mg vitamin E, and 2.5 or 5 mg riboflavin per kg. Feed supplementation enhanced the cytotoxic reaction and elevated the antibody titres produced against purified horse gamma globulin antigen. However, as compared to the control the differences were not significant. Feed supplementation exerted a beneficial, though varying, influence on the indices of cell-mediated immunity. The proportion of rosette-forming cells and blastogenic transformation induced by specific (horse globulin) and nonspecific (phytohaemagglutinin, PHA) mitogens underwent the most expressed and most significant increase in pigs fed 5 mg selenium, 100 mg vitamin E and 5 mg rivoflavin per kg of feed. On the other hand, feed supplementation failed to enhance the responsiveness to intradermal PHA (type IV allergic reaction).</description><identifier>ISSN: 0236-6290</identifier><identifier>PMID: 2627010</identifier><language>eng</language><publisher>Hungary</publisher><subject>ADDITIF AUX ALIMENTS DES ANIMAUX ; ADITIVO DE PIENSOS ; ALIMENTACION COMPLEMENTARIA ; ALIMENTACION DE LOS ANIMALES ; ALIMENTATION COMPLEMENTAIRE ; ALIMENTATION DES ANIMAUX ; Animal Feed ; Animals ; Antibody Formation ; CERDO ; DESTETE ; Female ; Immunity, Cellular ; LECHON ; Male ; PORCELET ; PORCIN ; REPONSE IMMUNITAIRE ; RESPUESTA INMUNOLOGICA ; Riboflavin - administration & dosage ; RIBOFLAVINA ; RIBOFLAVINE ; SELENIO ; SELENIUM ; Selenium - administration & dosage ; SEVRAGE ; Swine - immunology ; TOCOFEROLES ; TOCOPHEROL ; Vitamin E - administration & dosage ; VITAMINA E ; VITAMINE E</subject><ispartof>Acta veterinaria Hungarica (Budapest. 1983), 1989, Vol.37 (3), p.201-217</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2627010$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rafai, P</creatorcontrib><creatorcontrib>Tuboly, S</creatorcontrib><creatorcontrib>Jakab, L</creatorcontrib><creatorcontrib>Papp, Z</creatorcontrib><creatorcontrib>Molnar, L. (University of Veterinary Sciences, Budapest (Hungary))</creatorcontrib><creatorcontrib>Biro, H. (KA-HYB Pig Breeding and Marketing Co., Kaposvar (Hungary))</creatorcontrib><title>Effect of selenium, vitamin E and riboflavin supplementation of the feed on the humoral and cell-mediated immune responses of growing pigs</title><title>Acta veterinaria Hungarica (Budapest. 1983)</title><addtitle>Acta Vet Hung</addtitle><description>The feed of weaned piglets of Hungarian Large White X Duroc genotype was supplemented with 0.5 mg selenium, 50, 100 or 150 mg vitamin E, and 2.5 or 5 mg riboflavin per kg. Feed supplementation enhanced the cytotoxic reaction and elevated the antibody titres produced against purified horse gamma globulin antigen. However, as compared to the control the differences were not significant. Feed supplementation exerted a beneficial, though varying, influence on the indices of cell-mediated immunity. The proportion of rosette-forming cells and blastogenic transformation induced by specific (horse globulin) and nonspecific (phytohaemagglutinin, PHA) mitogens underwent the most expressed and most significant increase in pigs fed 5 mg selenium, 100 mg vitamin E and 5 mg rivoflavin per kg of feed. On the other hand, feed supplementation failed to enhance the responsiveness to intradermal PHA (type IV allergic reaction).</description><subject>ADDITIF AUX ALIMENTS DES ANIMAUX</subject><subject>ADITIVO DE PIENSOS</subject><subject>ALIMENTACION COMPLEMENTARIA</subject><subject>ALIMENTACION DE LOS ANIMALES</subject><subject>ALIMENTATION COMPLEMENTAIRE</subject><subject>ALIMENTATION DES ANIMAUX</subject><subject>Animal Feed</subject><subject>Animals</subject><subject>Antibody Formation</subject><subject>CERDO</subject><subject>DESTETE</subject><subject>Female</subject><subject>Immunity, Cellular</subject><subject>LECHON</subject><subject>Male</subject><subject>PORCELET</subject><subject>PORCIN</subject><subject>REPONSE IMMUNITAIRE</subject><subject>RESPUESTA INMUNOLOGICA</subject><subject>Riboflavin - administration & dosage</subject><subject>RIBOFLAVINA</subject><subject>RIBOFLAVINE</subject><subject>SELENIO</subject><subject>SELENIUM</subject><subject>Selenium - administration & dosage</subject><subject>SEVRAGE</subject><subject>Swine - immunology</subject><subject>TOCOFEROLES</subject><subject>TOCOPHEROL</subject><subject>Vitamin E - administration & dosage</subject><subject>VITAMINA E</subject><subject>VITAMINE E</subject><issn>0236-6290</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1ULtOwzAUzQAqpfADSEiemIjk2IkTj6gqFKkSC50jJ75OjWI72E4Rv8BXk9CuTPdxHvdxkSwxoSxlhOOr5DqED4xJlWOySBaEkRJneJn8bJSCNiKnUIAerB7NIzrqKIy2aIOElcjrxqleHKdGGIehBwM2iqidnVXxAEgBSDSVc34YjfOi_1O20PepAalFnAjamNEC8hAGZwOEWd1596VthwbdhZvkUok-wO05rpL98-Z9vU13by-v66ddqkiex5TJNhecVhwKNs2VjeK0VW1WsYrJghUKilKWGFhRYs5AUKZ4o5oCZ0BbSThdJQ8n38G7zxFCrI0O86rCghtDXfK8YiTLJuL9mTg20xX14LUR_rs-P2_C7064Eq4Wndeh3u55hnHGyn9AjDHNc_oLcy19Dg</recordid><startdate>1989</startdate><enddate>1989</enddate><creator>Rafai, P</creator><creator>Tuboly, S</creator><creator>Jakab, L</creator><creator>Papp, Z</creator><creator>Molnar, L. (University of Veterinary Sciences, Budapest (Hungary))</creator><creator>Biro, H. (KA-HYB Pig Breeding and Marketing Co., Kaposvar (Hungary))</creator><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>1989</creationdate><title>Effect of selenium, vitamin E and riboflavin supplementation of the feed on the humoral and cell-mediated immune responses of growing pigs</title><author>Rafai, P ; Tuboly, S ; Jakab, L ; Papp, Z ; Molnar, L. (University of Veterinary Sciences, Budapest (Hungary)) ; Biro, H. (KA-HYB Pig Breeding and Marketing Co., Kaposvar (Hungary))</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-f244t-6dc4a9389e56eeddbf93cfc18686d565fe57d70e657096ea36f9bfb501e3cd293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>ADDITIF AUX ALIMENTS DES ANIMAUX</topic><topic>ADITIVO DE PIENSOS</topic><topic>ALIMENTACION COMPLEMENTARIA</topic><topic>ALIMENTACION DE LOS ANIMALES</topic><topic>ALIMENTATION COMPLEMENTAIRE</topic><topic>ALIMENTATION DES ANIMAUX</topic><topic>Animal Feed</topic><topic>Animals</topic><topic>Antibody Formation</topic><topic>CERDO</topic><topic>DESTETE</topic><topic>Female</topic><topic>Immunity, Cellular</topic><topic>LECHON</topic><topic>Male</topic><topic>PORCELET</topic><topic>PORCIN</topic><topic>REPONSE IMMUNITAIRE</topic><topic>RESPUESTA INMUNOLOGICA</topic><topic>Riboflavin - administration & dosage</topic><topic>RIBOFLAVINA</topic><topic>RIBOFLAVINE</topic><topic>SELENIO</topic><topic>SELENIUM</topic><topic>Selenium - administration & dosage</topic><topic>SEVRAGE</topic><topic>Swine - immunology</topic><topic>TOCOFEROLES</topic><topic>TOCOPHEROL</topic><topic>Vitamin E - administration & dosage</topic><topic>VITAMINA E</topic><topic>VITAMINE E</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rafai, P</creatorcontrib><creatorcontrib>Tuboly, S</creatorcontrib><creatorcontrib>Jakab, L</creatorcontrib><creatorcontrib>Papp, Z</creatorcontrib><creatorcontrib>Molnar, L. (University of Veterinary Sciences, Budapest (Hungary))</creatorcontrib><creatorcontrib>Biro, H. (KA-HYB Pig Breeding and Marketing Co., Kaposvar (Hungary))</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Acta veterinaria Hungarica (Budapest. 1983)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rafai, P</au><au>Tuboly, S</au><au>Jakab, L</au><au>Papp, Z</au><au>Molnar, L. (University of Veterinary Sciences, Budapest (Hungary))</au><au>Biro, H. (KA-HYB Pig Breeding and Marketing Co., Kaposvar (Hungary))</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of selenium, vitamin E and riboflavin supplementation of the feed on the humoral and cell-mediated immune responses of growing pigs</atitle><jtitle>Acta veterinaria Hungarica (Budapest. 1983)</jtitle><addtitle>Acta Vet Hung</addtitle><date>1989</date><risdate>1989</risdate><volume>37</volume><issue>3</issue><spage>201</spage><epage>217</epage><pages>201-217</pages><issn>0236-6290</issn><abstract>The feed of weaned piglets of Hungarian Large White X Duroc genotype was supplemented with 0.5 mg selenium, 50, 100 or 150 mg vitamin E, and 2.5 or 5 mg riboflavin per kg. Feed supplementation enhanced the cytotoxic reaction and elevated the antibody titres produced against purified horse gamma globulin antigen. However, as compared to the control the differences were not significant. Feed supplementation exerted a beneficial, though varying, influence on the indices of cell-mediated immunity. The proportion of rosette-forming cells and blastogenic transformation induced by specific (horse globulin) and nonspecific (phytohaemagglutinin, PHA) mitogens underwent the most expressed and most significant increase in pigs fed 5 mg selenium, 100 mg vitamin E and 5 mg rivoflavin per kg of feed. On the other hand, feed supplementation failed to enhance the responsiveness to intradermal PHA (type IV allergic reaction).</abstract><cop>Hungary</cop><pmid>2627010</pmid><tpages>17</tpages></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
subjects | ADDITIF AUX ALIMENTS DES ANIMAUX ADITIVO DE PIENSOS ALIMENTACION COMPLEMENTARIA ALIMENTACION DE LOS ANIMALES ALIMENTATION COMPLEMENTAIRE ALIMENTATION DES ANIMAUX Animal Feed Animals Antibody Formation CERDO DESTETE Female Immunity, Cellular LECHON Male PORCELET PORCIN REPONSE IMMUNITAIRE RESPUESTA INMUNOLOGICA Riboflavin - administration & dosage RIBOFLAVINA RIBOFLAVINE SELENIO SELENIUM Selenium - administration & dosage SEVRAGE Swine - immunology TOCOFEROLES TOCOPHEROL Vitamin E - administration & dosage VITAMINA E VITAMINE E |
title | Effect of selenium, vitamin E and riboflavin supplementation of the feed on the humoral and cell-mediated immune responses of growing pigs |
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