Reaction Engineering for Consecutive Enzymatic Reactions in Peptide Synthesis: Application to the Synthesis of a Pentapeptide

A single‐pot enzymatic synthesis of Z‐CCK5 (4–8) is presented in this work, employing Z‐Gly‐Trp‐OBzl as acyl donor, under kinetic control. The first goal of the work is the development of a synthetic strategy allowing the use of the same medium for two reactions catalyzed by immobilized α‐chymotryps...

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