Alternative translation of the proto-oncogene c-myc by an internal ribosome entry site

The human proto-oncogene c-myc encodes two proteins, c-Myc1 and c-Myc2, from two initiation codons, CUG and AUG, respectively. It is also transcribed from four alternative promoters (P0, P1, P2, and P3), giving rise to different RNA 5'-leader sequences, the long sizes of which suggest that they...

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Veröffentlicht in:	The Journal of biological chemistry 1997-12, Vol.272 (51), p.32061-32066
Hauptverfasser:	Nanbru, C, Lafon, I, Audigier, S, Gensac, M C, Vagner, S, Huez, G, Prats, A C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Chloramphenicol O-Acetyltransferase - genetics Codon COS Cells Genes, myc Humans Molecular Sequence Data Nucleic Acid Conformation Promoter Regions, Genetic Protein Biosynthesis Recombinant Fusion Proteins - genetics Ribosomes - metabolism RNA Caps RNA, Messenger - chemistry RNA, Messenger - genetics Sequence Homology, Nucleic Acid Tumor Cells, Cultured
Online-Zugang:	Volltext
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