Genetic linkage study of a major susceptibility locus (D2S125) in a British population of non-insulin dependent diabetic sib-pairs using a simple non-isotopic screening method

A polymorphic microsatellite marker (D2S125) was recently reported to show significant linkage to non-insulin dependent diabetes mellitus (NIDDM) in a population of Mexican-American affected sib-pairs. We have used a simple non-isotopic screening technique employing the polymerase chain reaction (PC...

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Veröffentlicht in:	Human genetics 1997-12, Vol.101 (2), p.212-213
Hauptverfasser:	THOMAS, A. W, SHERRATT, E. J, GAGG, J. W, DAVIES, S. A, MAJID, A, ALCOLADO, J. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance Disease Susceptibility Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Genetic Linkage Genetic Testing - methods Humans Medical sciences Microsatellite Repeats Nuclear Family United Kingdom - epidemiology
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