Deficient oxidation of trihydroxycoprostanic acid in liver homogenates from patients with peroxisomal diseases

Summary The activation of palmitate and trihydroxycoprostanic acid and the peroxisomal oxidation of palmitate, trihydroxycoprostanic acid and their CoA esters were measured in homogenates prepared from fresh liver tissue of patients undergoing hepatic surgery and from frozen postmortem liver specime...

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Veröffentlicht in:	Journal of inherited metabolic disease 1989-12, Vol.12 (4), p.415-422
Hauptverfasser:	Casteels, M., Van Roermund, C. W. T., Schepers, L., Govaert, L., Eyssen, H. J., Mannaerts, G. P., Wanders, R. J. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl-CoA C-Acetyltransferase - deficiency Acetyl-CoA C-Acetyltransferase - metabolism Acetyltransferases - deficiency Biological and medical sciences Cholic Acids - metabolism Errors of metabolism Humans Lipid Peroxidation Liver - enzymology Medical sciences Metabolic diseases Microbodies - enzymology Miscellaneous hereditary metabolic disorders Substrate Specificity Zellweger Syndrome - enzymology Zellweger Syndrome - metabolism
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