[44] Gangliosides that modulate membrane protein function
This chapter discusses the effect of gangliosides on cell growth and the associated modulatory effects of gangliosides on receptor-associated tyrosine kinase, protein kinase C, and other kinases. The effect of gangliosides as differentiation inducers for hematopoietic cells is also described in the...
Gespeichert in:
| Veröffentlicht in: | Methods in Enzymology 1989, Vol.179, p.521-541 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 541 |
|---|---|
| container_issue | |
| container_start_page | 521 |
| container_title | Methods in Enzymology |
| container_volume | 179 |
| creator | Igarashi, Yasuyuki Nojiri, Hisao Hanai, Nobuo Hakomori, Sen-itiroh |
| description | This chapter discusses the effect of gangliosides on cell growth and the associated modulatory effects of gangliosides on receptor-associated tyrosine kinase, protein kinase C, and other kinases. The effect of gangliosides as differentiation inducers for hematopoietic cells is also described in the chapter. The chapter discusses the differentiation induction by gangliosides of human promyelocytic leukemia cell line I-IL60 cells into monocytes/macrophages or neutrophilic mature granulocytes. Results from these experimental systems have been interpreted to suggest that gangliosides by themselves may transduce signals stimulating or inhibiting cell growth, or may modulate cell growth through influencing the function of receptors, transducers, or transporters that are essential for cell growth regulation. |
| doi_str_mv | 10.1016/0076-6879(89)79152-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_79470161</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0076687989791527</els_id><sourcerecordid>79470161</sourcerecordid><originalsourceid>FETCH-LOGICAL-e291t-defe8627d501559e769e69634e9414ee1a5a4250bda4e65692236913c1dc89ad3</originalsourceid><addsrcrecordid>eNo9kUtLAzEQx4MPtNZ-A4W9KHpYTbKbx1wEKVqFghc9iYQ0mWpkH3WzK_jtTbV0LnOYH8P_QcgJo1eMMnlNqZK51AouNFwqYILnaoeMmBAqV6D1LjmijDPNqaZqj4y2_CGZxPhJ0wiluFQH5IALSVlBRwRey_Itm9nmvQptDB5j1n_YPqtbP1S2x6zGetHZBrNV1_YYmmw5NK4PbXNM9pe2ijjZ7DF5ub97nj7k86fZ4_R2niMH1ucel6glV17QpBRQSUAJsigRSlYiMitsyQVdeFuiFBI4LySwwjHvNFhfjMn5_98k4GvA2Js6RIdVlUS1QzQKSpXiYQk83YDDokZvVl2obfdjNl7T_Wxzt9HZaplcuRC3GAMOVHJI3M0_h8nVd8DORBewcehDh643vg2GUbPuxKwzNuuMjQbz14lRxS9KRnjG</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79470161</pqid></control><display><type>article</type><title>[44] Gangliosides that modulate membrane protein function</title><source>MEDLINE</source><source>ScienceDirect eBooks</source><source>Access via ScienceDirect (Elsevier)</source><creator>Igarashi, Yasuyuki ; Nojiri, Hisao ; Hanai, Nobuo ; Hakomori, Sen-itiroh</creator><creatorcontrib>Igarashi, Yasuyuki ; Nojiri, Hisao ; Hanai, Nobuo ; Hakomori, Sen-itiroh</creatorcontrib><description>This chapter discusses the effect of gangliosides on cell growth and the associated modulatory effects of gangliosides on receptor-associated tyrosine kinase, protein kinase C, and other kinases. The effect of gangliosides as differentiation inducers for hematopoietic cells is also described in the chapter. The chapter discusses the differentiation induction by gangliosides of human promyelocytic leukemia cell line I-IL60 cells into monocytes/macrophages or neutrophilic mature granulocytes. Results from these experimental systems have been interpreted to suggest that gangliosides by themselves may transduce signals stimulating or inhibiting cell growth, or may modulate cell growth through influencing the function of receptors, transducers, or transporters that are essential for cell growth regulation.</description><identifier>ISSN: 0076-6879</identifier><identifier>ISBN: 0121820807</identifier><identifier>ISBN: 9780121820800</identifier><identifier>EISSN: 1557-7988</identifier><identifier>DOI: 10.1016/0076-6879(89)79152-7</identifier><identifier>PMID: 2560130</identifier><identifier>CODEN: MENZAU</identifier><language>eng</language><publisher>San Diego, CA: Elsevier Science & Technology</publisher><subject>Analytical, structural and metabolic biochemistry ; Animals ; Biological and medical sciences ; Cell Division - drug effects ; Cell Line ; Cell Membrane - drug effects ; Cell Membrane - physiology ; Cells, Cultured ; ErbB Receptors - drug effects ; ErbB Receptors - metabolism ; Fundamental and applied biological sciences. Psychology ; G(M1) Ganglioside - pharmacology ; G(M3) Ganglioside - pharmacology ; Gangliosides - pharmacology ; Gangliosides - physiology ; Kinetics ; Lipids ; Membrane Proteins - drug effects ; Membrane Proteins - metabolism ; Membrane Proteins - physiology ; Mice ; Other biological molecules ; Phosphorylation ; Platelet-Derived Growth Factor - pharmacology ; Protein Kinase C - metabolism ; Protein Kinases - metabolism ; Protein-Tyrosine Kinases - metabolism ; Receptors, Platelet-Derived Growth Factor ; Sphingolipids</subject><ispartof>Methods in Enzymology, 1989, Vol.179, p.521-541</ispartof><rights>1989</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0076687989791527$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,780,781,785,794,3460,3551,4025,11293,27928,27929,27930,45815,46000</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19290629$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2560130$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Igarashi, Yasuyuki</creatorcontrib><creatorcontrib>Nojiri, Hisao</creatorcontrib><creatorcontrib>Hanai, Nobuo</creatorcontrib><creatorcontrib>Hakomori, Sen-itiroh</creatorcontrib><title>[44] Gangliosides that modulate membrane protein function</title><title>Methods in Enzymology</title><addtitle>Methods Enzymol</addtitle><description>This chapter discusses the effect of gangliosides on cell growth and the associated modulatory effects of gangliosides on receptor-associated tyrosine kinase, protein kinase C, and other kinases. The effect of gangliosides as differentiation inducers for hematopoietic cells is also described in the chapter. The chapter discusses the differentiation induction by gangliosides of human promyelocytic leukemia cell line I-IL60 cells into monocytes/macrophages or neutrophilic mature granulocytes. Results from these experimental systems have been interpreted to suggest that gangliosides by themselves may transduce signals stimulating or inhibiting cell growth, or may modulate cell growth through influencing the function of receptors, transducers, or transporters that are essential for cell growth regulation.</description><subject>Analytical, structural and metabolic biochemistry</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Cell Division - drug effects</subject><subject>Cell Line</subject><subject>Cell Membrane - drug effects</subject><subject>Cell Membrane - physiology</subject><subject>Cells, Cultured</subject><subject>ErbB Receptors - drug effects</subject><subject>ErbB Receptors - metabolism</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>G(M1) Ganglioside - pharmacology</subject><subject>G(M3) Ganglioside - pharmacology</subject><subject>Gangliosides - pharmacology</subject><subject>Gangliosides - physiology</subject><subject>Kinetics</subject><subject>Lipids</subject><subject>Membrane Proteins - drug effects</subject><subject>Membrane Proteins - metabolism</subject><subject>Membrane Proteins - physiology</subject><subject>Mice</subject><subject>Other biological molecules</subject><subject>Phosphorylation</subject><subject>Platelet-Derived Growth Factor - pharmacology</subject><subject>Protein Kinase C - metabolism</subject><subject>Protein Kinases - metabolism</subject><subject>Protein-Tyrosine Kinases - metabolism</subject><subject>Receptors, Platelet-Derived Growth Factor</subject><subject>Sphingolipids</subject><issn>0076-6879</issn><issn>1557-7988</issn><isbn>0121820807</isbn><isbn>9780121820800</isbn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kUtLAzEQx4MPtNZ-A4W9KHpYTbKbx1wEKVqFghc9iYQ0mWpkH3WzK_jtTbV0LnOYH8P_QcgJo1eMMnlNqZK51AouNFwqYILnaoeMmBAqV6D1LjmijDPNqaZqj4y2_CGZxPhJ0wiluFQH5IALSVlBRwRey_Itm9nmvQptDB5j1n_YPqtbP1S2x6zGetHZBrNV1_YYmmw5NK4PbXNM9pe2ijjZ7DF5ub97nj7k86fZ4_R2niMH1ucel6glV17QpBRQSUAJsigRSlYiMitsyQVdeFuiFBI4LySwwjHvNFhfjMn5_98k4GvA2Js6RIdVlUS1QzQKSpXiYQk83YDDokZvVl2obfdjNl7T_Wxzt9HZaplcuRC3GAMOVHJI3M0_h8nVd8DORBewcehDh643vg2GUbPuxKwzNuuMjQbz14lRxS9KRnjG</recordid><startdate>1989</startdate><enddate>1989</enddate><creator>Igarashi, Yasuyuki</creator><creator>Nojiri, Hisao</creator><creator>Hanai, Nobuo</creator><creator>Hakomori, Sen-itiroh</creator><general>Elsevier Science & Technology</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>1989</creationdate><title>[44] Gangliosides that modulate membrane protein function</title><author>Igarashi, Yasuyuki ; Nojiri, Hisao ; Hanai, Nobuo ; Hakomori, Sen-itiroh</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-e291t-defe8627d501559e769e69634e9414ee1a5a4250bda4e65692236913c1dc89ad3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Analytical, structural and metabolic biochemistry</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Cell Division - drug effects</topic><topic>Cell Line</topic><topic>Cell Membrane - drug effects</topic><topic>Cell Membrane - physiology</topic><topic>Cells, Cultured</topic><topic>ErbB Receptors - drug effects</topic><topic>ErbB Receptors - metabolism</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>G(M1) Ganglioside - pharmacology</topic><topic>G(M3) Ganglioside - pharmacology</topic><topic>Gangliosides - pharmacology</topic><topic>Gangliosides - physiology</topic><topic>Kinetics</topic><topic>Lipids</topic><topic>Membrane Proteins - drug effects</topic><topic>Membrane Proteins - metabolism</topic><topic>Membrane Proteins - physiology</topic><topic>Mice</topic><topic>Other biological molecules</topic><topic>Phosphorylation</topic><topic>Platelet-Derived Growth Factor - pharmacology</topic><topic>Protein Kinase C - metabolism</topic><topic>Protein Kinases - metabolism</topic><topic>Protein-Tyrosine Kinases - metabolism</topic><topic>Receptors, Platelet-Derived Growth Factor</topic><topic>Sphingolipids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Igarashi, Yasuyuki</creatorcontrib><creatorcontrib>Nojiri, Hisao</creatorcontrib><creatorcontrib>Hanai, Nobuo</creatorcontrib><creatorcontrib>Hakomori, Sen-itiroh</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Methods in Enzymology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Igarashi, Yasuyuki</au><au>Nojiri, Hisao</au><au>Hanai, Nobuo</au><au>Hakomori, Sen-itiroh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>[44] Gangliosides that modulate membrane protein function</atitle><jtitle>Methods in Enzymology</jtitle><addtitle>Methods Enzymol</addtitle><date>1989</date><risdate>1989</risdate><volume>179</volume><spage>521</spage><epage>541</epage><pages>521-541</pages><issn>0076-6879</issn><eissn>1557-7988</eissn><isbn>0121820807</isbn><isbn>9780121820800</isbn><coden>MENZAU</coden><abstract>This chapter discusses the effect of gangliosides on cell growth and the associated modulatory effects of gangliosides on receptor-associated tyrosine kinase, protein kinase C, and other kinases. The effect of gangliosides as differentiation inducers for hematopoietic cells is also described in the chapter. The chapter discusses the differentiation induction by gangliosides of human promyelocytic leukemia cell line I-IL60 cells into monocytes/macrophages or neutrophilic mature granulocytes. Results from these experimental systems have been interpreted to suggest that gangliosides by themselves may transduce signals stimulating or inhibiting cell growth, or may modulate cell growth through influencing the function of receptors, transducers, or transporters that are essential for cell growth regulation.</abstract><cop>San Diego, CA</cop><pub>Elsevier Science & Technology</pub><pmid>2560130</pmid><doi>10.1016/0076-6879(89)79152-7</doi><tpages>21</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0076-6879 |
| ispartof | Methods in Enzymology, 1989, Vol.179, p.521-541 |
| issn | 0076-6879 1557-7988 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79470161 |
| source | MEDLINE; ScienceDirect eBooks; Access via ScienceDirect (Elsevier) |
| subjects | Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Cell Division - drug effects Cell Line Cell Membrane - drug effects Cell Membrane - physiology Cells, Cultured ErbB Receptors - drug effects ErbB Receptors - metabolism Fundamental and applied biological sciences. Psychology G(M1) Ganglioside - pharmacology G(M3) Ganglioside - pharmacology Gangliosides - pharmacology Gangliosides - physiology Kinetics Lipids Membrane Proteins - drug effects Membrane Proteins - metabolism Membrane Proteins - physiology Mice Other biological molecules Phosphorylation Platelet-Derived Growth Factor - pharmacology Protein Kinase C - metabolism Protein Kinases - metabolism Protein-Tyrosine Kinases - metabolism Receptors, Platelet-Derived Growth Factor Sphingolipids |
| title | [44] Gangliosides that modulate membrane protein function |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T09%3A01%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=%5B44%5D%20Gangliosides%20that%20modulate%20membrane%20protein%20function&rft.jtitle=Methods%20in%20Enzymology&rft.au=Igarashi,%20Yasuyuki&rft.date=1989&rft.volume=179&rft.spage=521&rft.epage=541&rft.pages=521-541&rft.issn=0076-6879&rft.eissn=1557-7988&rft.isbn=0121820807&rft.isbn_list=9780121820800&rft.coden=MENZAU&rft_id=info:doi/10.1016/0076-6879(89)79152-7&rft_dat=%3Cproquest_pubme%3E79470161%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79470161&rft_id=info:pmid/2560130&rft_els_id=0076687989791527&rfr_iscdi=true |