Two NFAT Transcription Factor Binding Sites Participate in the Regulation of CD95 (Fas) Ligand Expression in Activated Human T Cells

Antigen receptor engagement on T lymphocytes activates transcription factors important for stimulating cytokine gene expression. This is critical for clonal expansion of antigen-specific T cells and propagation of immune responses. Additionally, under some conditions antigen receptor stimulation ini...

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Veröffentlicht in:	The Journal of biological chemistry 1997-12, Vol.272 (50), p.31427-31434
Hauptverfasser:	Latinis, Kevin M., Norian, Lyse A., Eliason, Steve L., Koretzky, Gary A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites DNA Footprinting DNA Mutational Analysis DNA-Binding Proteins - metabolism Fas Ligand Protein fas Receptor - genetics fas Receptor - metabolism Humans Jurkat Cells Male Membrane Glycoproteins - metabolism NFATC Transcription Factors Nuclear Proteins - metabolism Phosphoproteins - metabolism Promoter Regions, Genetic Protein Binding Sertoli Cells - chemistry T-Lymphocytes - metabolism Transcription Factors - metabolism
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