Effects of repeated apomorphine and haloperidol treatments on subsequent behavioral sensitivity to apomorphine

In a 2 × 2 factorial design, four groups of rats (n=10 each) were injected daily with haloperidol (0.5 mg/kg IP) or its injection vehicle and apomorphine (1.0 mg/kg SC) or its vehicle for 21 consecutive days. Then, following a six-day drug-free rest interval, all rats were tested for locomotor activ...

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Veröffentlicht in:Pharmacology, biochemistry and behavior biochemistry and behavior, 1989-10, Vol.34 (2), p.345-347
Hauptverfasser: Mattingly, Bruce A., Rowlett, James K.
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Sprache:eng
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