Sex Differences in the Abundance of Endothelial Nitric Oxide in a Model of Genetic Hypertension

A deficiency of nitric oxide may be responsible for the increased vascular resistance associated with human essential hypertension and that seen in animal models of hypertension. Premenopausal females are relatively protected from hypertension and cardiovascular complications. Levels of superoxide c...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 1997-12, Vol.30 (6), p.1517-1524
Hauptverfasser:	McIntyre, Martin, Hamilton, Carlene A, Rees, Daryl D, Reid, John L, Dominiczak, Anna F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta, Thoracic - drug effects Aorta, Thoracic - physiology Aorta, Thoracic - physiopathology Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure Body Weight Carbachol - pharmacology Cardiology. Vascular system Cerebrovascular Disorders Ditiocarb - pharmacology Endothelium, Vascular - enzymology Endothelium, Vascular - metabolism Experimental diseases Female Humans Hypertension - genetics Hypertension - physiopathology In Vitro Techniques Indomethacin - pharmacology Isometric Contraction - drug effects Male Medical sciences Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - physiology Muscle, Smooth, Vascular - physiopathology NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide - metabolism Nitric Oxide Synthase - metabolism Phenylephrine - pharmacology Potassium Chloride - pharmacology Rats Rats, Inbred SHR Rats, Inbred WKY Sex Characteristics Systole
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