The T-cell Receptor as Immunoglobulin: Paradigm Regained

Abstract The quest to determine the molecular nature of T-lymphocyte receptors for antigen was a “holy grail” to immunologists for over 25 years. This paper updates a review written 15 years ago (Marchalonis JJ, Hunt JC. Proc Soc Exp Biol Med 171:127-145, 1982), which proposed that “these molecules...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1997-12, Vol.216 (3), p.303-318
Hauptverfasser:	Marchalonis, John J., Schluter, Samuel F., Edmundson, Allen B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cross Reactions Histocompatibility Antigens - metabolism History of medicine History, 20th Century Humans Immunoglobulins - chemistry Immunoglobulins - genetics Immunoglobulins - history Immunoglobulins - metabolism Models, Molecular Molecular Sequence Data Peptides - metabolism Protein Binding Receptors, Antigen, T-Cell - chemistry Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - history Receptors, Antigen, T-Cell - metabolism Sequence Alignment Sequence Analysis, DNA Sequence Homology, Amino Acid Superantigens - metabolism
Online-Zugang:	Volltext
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