Angiographic assessment of human coronary artery endothelial function by measurement of endothelium-dependent vasodilation

In isolated atherosclerotic human coronary arteries endothelium-dependent vascular relaxation is abolished with acetylcholine whereas another EDRF-dependent vasodilator, substance P, still produces significant relaxation. To study further these in vitro findings, graded doses of acetylcholine and su...

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Veröffentlicht in:	European heart journal 1989-11, Vol.10 (suppl-F), p.44-48
Hauptverfasser:	Bossaller, C., Hehlert-Friedrich, C., Jost, S., Rafflenbeul, W., Lichtlen, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Adult angiography atherosclerosis Coronary Angiography Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - physiopathology Coronary Vessels - drug effects Coronary Vessels - physiology Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Endothelium-dependent human coronary artery Humans Male Middle Aged Nitroglycerin - pharmacology Oxygen Consumption - drug effects Radiographic Image Enhancement Substance P - pharmacology vasodilation Vasodilation - drug effects Vasodilation - physiology
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