Structural Studies of Detergent-Solubilized and Vesicle-Reconstituted Low-Density Lipoprotein (LDL) Receptor

The low-density lipoprotein (LDL) receptor plays a key role in maintaining circulating and cellular cholesterol homeostasis. The LDL receptor is a transmembrane glycoprotein whose biochemical and genetic properties have been extensively studied notably by Brown, Goldstein and colleagues [Brown, M. S...

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Veröffentlicht in:	Biochemistry (Easton) 1997-12, Vol.36 (50), p.15940-15948
Hauptverfasser:	Saxena, Kumkum, Shipley, G. Graham
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex - chemistry Algorithms Amino Acid Sequence Animals Cattle Chromatography, Affinity Circular Dichroism Detergents Guanidine Humans Lipoproteins, LDL - metabolism Liposomes - metabolism Luminescent Measurements Membrane Glycoproteins - chemistry Microscopy, Electron Molecular Sequence Data Phosphatidylcholines - metabolism Protein Binding Protein Folding Protein Structure, Secondary Receptors, LDL - chemistry Receptors, LDL - isolation & purification Solubility Temperature
Online-Zugang:	Volltext
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