Modulation of porcine granulosa cell functions by interleukin-1
Increasing evidence suggests that functions of the immune system and gonads are closely related with each other. In cultures of granulosa and luteal cells, macrophages have been shown to modulate steroidogenic functions. In this paper we present the modulatory effects of interleukin-1, a cytokine pr...
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Veröffentlicht in: | Steroids 1989-11, Vol.54 (5), p.543-552 |
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creator | Mori, Takahide Fukuoka, Masatsune Yasuda, Keiko Takakura, Kenji Iwai, Toshiko Taii, Shunzo |
description | Increasing evidence suggests that functions of the immune system and gonads are closely related with each other. In cultures of granulosa and luteal cells, macrophages have been shown to modulate steroidogenic functions. In this paper we present the modulatory effects of interleukin-1, a cytokine produced predominantly by activated macrophages, on gonadotropin-induced differentiation, as well as growth of cultured porcine granulosa cells. |
doi_str_mv | 10.1016/0039-128X(89)90046-9 |
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In cultures of granulosa and luteal cells, macrophages have been shown to modulate steroidogenic functions. In this paper we present the modulatory effects of interleukin-1, a cytokine produced predominantly by activated macrophages, on gonadotropin-induced differentiation, as well as growth of cultured porcine granulosa cells.</description><identifier>ISSN: 0039-128X</identifier><identifier>EISSN: 1878-5867</identifier><identifier>DOI: 10.1016/0039-128X(89)90046-9</identifier><identifier>PMID: 2559501</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Cell Differentiation ; Cells, Cultured ; Cyclic AMP - metabolism ; Dose-Response Relationship, Drug ; Female ; Follicle Stimulating Hormone - pharmacology ; Granulosa Cells - drug effects ; Granulosa Cells - physiology ; Interleukin-1 - administration & dosage ; Interleukin-1 - pharmacology ; Luteinizing Hormone - pharmacology ; Progesterone - antagonists & inhibitors ; Progesterone - metabolism ; Swine</subject><ispartof>Steroids, 1989-11, Vol.54 (5), p.543-552</ispartof><rights>1989</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c272t-a09261d84eccdfeeaaf83afdc186915b9fa8e24ee2934a2a3a3850a7aa3063533</citedby><cites>FETCH-LOGICAL-c272t-a09261d84eccdfeeaaf83afdc186915b9fa8e24ee2934a2a3a3850a7aa3063533</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0039-128X(89)90046-9$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2559501$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mori, Takahide</creatorcontrib><creatorcontrib>Fukuoka, Masatsune</creatorcontrib><creatorcontrib>Yasuda, Keiko</creatorcontrib><creatorcontrib>Takakura, Kenji</creatorcontrib><creatorcontrib>Iwai, Toshiko</creatorcontrib><creatorcontrib>Taii, Shunzo</creatorcontrib><title>Modulation of porcine granulosa cell functions by interleukin-1</title><title>Steroids</title><addtitle>Steroids</addtitle><description>Increasing evidence suggests that functions of the immune system and gonads are closely related with each other. 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In this paper we present the modulatory effects of interleukin-1, a cytokine produced predominantly by activated macrophages, on gonadotropin-induced differentiation, as well as growth of cultured porcine granulosa cells.</description><subject>Animals</subject><subject>Cell Differentiation</subject><subject>Cells, Cultured</subject><subject>Cyclic AMP - metabolism</subject><subject>Dose-Response Relationship, Drug</subject><subject>Female</subject><subject>Follicle Stimulating Hormone - pharmacology</subject><subject>Granulosa Cells - drug effects</subject><subject>Granulosa Cells - physiology</subject><subject>Interleukin-1 - administration & dosage</subject><subject>Interleukin-1 - pharmacology</subject><subject>Luteinizing Hormone - pharmacology</subject><subject>Progesterone - antagonists & inhibitors</subject><subject>Progesterone - metabolism</subject><subject>Swine</subject><issn>0039-128X</issn><issn>1878-5867</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtPwzAQhC0EglL4ByDlhOAQ8CNx7AsIVbykIi4gcbO2zhoZ0rjYCVL_PQ2teuS0h5mdnf0IOWH0klEmrygVOmdcvZ8rfaEpLWSud8iIqUrlpZLVLhltLQfkMKVPSqkUmu-TfV6WuqRsRG6eQ9030PnQZsFlixCtbzH7iND2TUiQWWyazPWtHSwpmy0z33YYG-y_fJuzI7LnoEl4vJlj8nZ_9zp5zKcvD0-T22luecW7HKjmktWqQGtrhwjglABXW6akZuVMO1DIC0SuRQEcBAhVUqgAxKpyKcSYnK1zFzF895g6M_dp6AYthj6ZShellHowFmujjSGliM4sop9DXBpGzcDNDFDMAMUobf64Gb1aO93k97M51tulDaiVfr3WcfXkj8dokvXYWqx9RNuZOvj_D_wCwpB9XA</recordid><startdate>198911</startdate><enddate>198911</enddate><creator>Mori, Takahide</creator><creator>Fukuoka, Masatsune</creator><creator>Yasuda, Keiko</creator><creator>Takakura, Kenji</creator><creator>Iwai, Toshiko</creator><creator>Taii, Shunzo</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198911</creationdate><title>Modulation of porcine granulosa cell functions by interleukin-1</title><author>Mori, Takahide ; Fukuoka, Masatsune ; Yasuda, Keiko ; Takakura, Kenji ; Iwai, Toshiko ; Taii, Shunzo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c272t-a09261d84eccdfeeaaf83afdc186915b9fa8e24ee2934a2a3a3850a7aa3063533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Animals</topic><topic>Cell Differentiation</topic><topic>Cells, Cultured</topic><topic>Cyclic AMP - metabolism</topic><topic>Dose-Response Relationship, Drug</topic><topic>Female</topic><topic>Follicle Stimulating Hormone - pharmacology</topic><topic>Granulosa Cells - drug effects</topic><topic>Granulosa Cells - physiology</topic><topic>Interleukin-1 - administration & dosage</topic><topic>Interleukin-1 - pharmacology</topic><topic>Luteinizing Hormone - pharmacology</topic><topic>Progesterone - antagonists & inhibitors</topic><topic>Progesterone - metabolism</topic><topic>Swine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mori, Takahide</creatorcontrib><creatorcontrib>Fukuoka, Masatsune</creatorcontrib><creatorcontrib>Yasuda, Keiko</creatorcontrib><creatorcontrib>Takakura, Kenji</creatorcontrib><creatorcontrib>Iwai, Toshiko</creatorcontrib><creatorcontrib>Taii, Shunzo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Steroids</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mori, Takahide</au><au>Fukuoka, Masatsune</au><au>Yasuda, Keiko</au><au>Takakura, Kenji</au><au>Iwai, Toshiko</au><au>Taii, Shunzo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Modulation of porcine granulosa cell functions by interleukin-1</atitle><jtitle>Steroids</jtitle><addtitle>Steroids</addtitle><date>1989-11</date><risdate>1989</risdate><volume>54</volume><issue>5</issue><spage>543</spage><epage>552</epage><pages>543-552</pages><issn>0039-128X</issn><eissn>1878-5867</eissn><abstract>Increasing evidence suggests that functions of the immune system and gonads are closely related with each other. In cultures of granulosa and luteal cells, macrophages have been shown to modulate steroidogenic functions. In this paper we present the modulatory effects of interleukin-1, a cytokine produced predominantly by activated macrophages, on gonadotropin-induced differentiation, as well as growth of cultured porcine granulosa cells.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>2559501</pmid><doi>10.1016/0039-128X(89)90046-9</doi><tpages>10</tpages></addata></record> |
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subjects | Animals Cell Differentiation Cells, Cultured Cyclic AMP - metabolism Dose-Response Relationship, Drug Female Follicle Stimulating Hormone - pharmacology Granulosa Cells - drug effects Granulosa Cells - physiology Interleukin-1 - administration & dosage Interleukin-1 - pharmacology Luteinizing Hormone - pharmacology Progesterone - antagonists & inhibitors Progesterone - metabolism Swine |
title | Modulation of porcine granulosa cell functions by interleukin-1 |
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