Allelic loss in childhood acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most frequent cancer encountered in children. Little is known about the molecular basis of childhood ALL, although the clinical, pathological, and immunophenotypic features have been well documented. To understand the role of tumor suppressor genes (TSGs) in...

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Veröffentlicht in:	Leukemia research 1997-09, Vol.21 (9), p.817-823
Hauptverfasser:	Baccichet, Annie, Qualman, Sarah K., Sinnett, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Alleles allelotype Biological and medical sciences Child Child, Preschool childhood acute lymphoblastic leukemia Chromosomes, Human - genetics DNA, Neoplasm - genetics Female Gene Deletion Genes, Tumor Suppressor Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Loss of Heterozygosity Male Medical sciences microsatellite Microsatellite Repeats Precursor Cell Lymphoblastic Leukemia-Lymphoma - classification Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics tumor suppressor gene
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