Modulation of Microglial form and Immune Function by Factors Released from Goldfish Optic Nerves

Activation of microglia is associated with neural damage and may aid repair of the CNS. To begin to investigate their role, microglia purified from mouse brain were grown in media conditioned (CM) by goldfish optic nerve (GFON), optic tectum (GFOT), vagal lobe, telencephalon and cerebellum, and medi...

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Veröffentlicht in:	International journal of neuroscience 1997-01, Vol.91 (1-2), p.133-146
Hauptverfasser:	Perry, G. W., Keane, Robert W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen Presentation Biological and medical sciences Carassius auratus Cell Size - immunology Cells, Cultured Culture Media, Conditioned Cytokines - immunology Cytokines - metabolism Development. Senescence. Regeneration. Transplantation Fluorescent Antibody Technique Freshwater Fundamental and applied biological sciences. Psychology Goldfish Histocompatibility Antigens Class II - immunology immune reactivity MHC expression Mice Mice, Inbred CBA Microglia Microglia - cytology Microglia - immunology Nerve Tissue - immunology Nerve Tissue - metabolism Neuroimmunomodulation optic nerve Optic Nerve - immunology Optic Nerve - metabolism rat Rats T-Lymphocytes, Helper-Inducer - immunology Vertebrates: nervous system and sense organs
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