Identification of Two Nervous System-Specific Members of the erg Potassium Channel Gene Family

Two new potassium channel genes, erg2 and erg3, that are expressed in the nervous system of the rat were identified. These two genes form a small gene family with the previously described erg1 (HERG) gene. The erg2 and erg3 genes are expressed exclusively in the nervous system, in marked contrast to...

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Veröffentlicht in:	The Journal of neuroscience 1997-12, Vol.17 (24), p.9423-9432
Hauptverfasser:	Shi, Wenmei, Wymore, Randy S, Wang, Hong-Sheng, Pan, Zongming, Cohen, Ira S, McKinnon, David, Dixon, Jane E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cation Transport Proteins Cloning, Molecular DNA, Complementary - isolation & purification DNA-Binding Proteins Electrophysiology ERG1 Potassium Channel Ether-A-Go-Go Potassium Channels Gene Expression - physiology Heart - innervation Humans Kinetics Long QT Syndrome - genetics Membrane Transport Proteins Molecular Sequence Data Neurons - chemistry Neurons - physiology Oocytes - physiology Potassium Channels - genetics Potassium Channels - metabolism Potassium Channels, Voltage-Gated Rats RNA, Messenger - analysis Sequence Homology, Amino Acid Sympathetic Nervous System - chemistry Sympathetic Nervous System - cytology Trans-Activators Transcriptional Regulator ERG Xenopus
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