Effects of estrogen replacement therapy on dehydroepiandrosterone, dehydroepiandrosterone sulfate, and cortisol responses to exercise in postmenopausal women
Objective: To determine the effects of hormone replacement therapy (HRT) drosterone (DHEA), DHEA sulfate (DHEAS), and cortisol (F) responses to treadmill exercise. Design: Controlled clinical study. Setting: Female volunteers in an academic research environment. Patient(s): Sixteen healthy, postmeno...
Gespeichert in:
| Veröffentlicht in: | Fertility and sterility 1997-11, Vol.68 (5), p.836-843 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 843 |
|---|---|
| container_issue | 5 |
| container_start_page | 836 |
| container_title | Fertility and sterility |
| container_volume | 68 |
| creator | Johnson, Lisa G. Kraemer, Robert R. Haltom, Ron Kraemer, Ginger R. Gaines, Helen E. Daniel Castracane, V. |
| description | Objective: To determine the effects of hormone replacement therapy (HRT) drosterone (DHEA), DHEA sulfate (DHEAS), and cortisol (F) responses to treadmill exercise.
Design: Controlled clinical study.
Setting: Female volunteers in an academic research environment.
Patient(s): Sixteen healthy, postmenopausal women (7 were receiving HRT, 9 were not).
Intervention(s): Blood samples were taken, from an intravenous cathether before, during, and after 30 minutes of treadmill exercise following an overnight fast. A second session was conducted one month later for the same subjects using the same blood sampling protocol without exercise.
Main Outcome Measure(s): Serum DHEA, DHEAS, and F concentrations.
Result(s): The HRT and untreated DHEA area under the curve (AUC) for the exercise trials was significantly greater than that for the control trials. The untreated, but not the HRT, DHEAS AUC for the exercise trials was significantly greater than that for the control trials. The HRT and untreated F AUC for the exercise trials was significantly greater than that for the control trials. The AUC for the HRT exercise trials was significantly higher than the untreated exercise trials for DHEA and F, but not DHEAS.
Conclusion(s): Data suggest that treadmill exercise elevates DHEA, DHEAS, and F levels in postmenopausal women and that HRT enhances the DHEA and F responses. |
| doi_str_mv | 10.1016/S0015-0282(97)00369-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79447068</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0015028297003695</els_id><sourcerecordid>79447068</sourcerecordid><originalsourceid>FETCH-LOGICAL-c436t-1ae3334e6cfe98213261597744576962095d6a7aaade193755befa20a8ed9bc3</originalsourceid><addsrcrecordid>eNqFUU2LFDEQDaKs4-pPWMhBRMHWfHSSzklkWT9gwYN7DzXpihvpSdqkW50f4381uzPMTTwVqfdeVeU9Qi44e8MZ12-_MsZVx8QgXlrzijGpbacekA1XSndKK_mQbE6Ux-RJrd8ZY5obcUbOrBzswMWG_LkKAf1SaQ4U61LyN0y04DyBxx2mhS63WGDe05zoiLf7sWScI6RW64IlJ3z9jz6t6xRgaXjrUp_LEmue2uw651Sx0iVT_I3Fx4o0Jjo3YduYZ1grTPRXbo-n5FGAqeKzYz0nNx-ubi4_dddfPn6-fH_d-V7qpeOAUsoetQ9oB8Gl0FxZY_peGW21YFaNGgwAjMitNEptMYBgMOBot16ekxeHsXPJP9Zmg9vF6nGaIGFeqzO27w3TQyOqA9G3b9aCwc0l7qDsHWfuLhV3n4q7s9xZ4-5TcarpLo4L1u0Ox5PqGEPDnx9xqB6mUCA1W040wfkge91o7w40bF78jFhc9RGTxzGWFqIbc_zPIX8BfBauOw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79447068</pqid></control><display><type>article</type><title>Effects of estrogen replacement therapy on dehydroepiandrosterone, dehydroepiandrosterone sulfate, and cortisol responses to exercise in postmenopausal women</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>Johnson, Lisa G. ; Kraemer, Robert R. ; Haltom, Ron ; Kraemer, Ginger R. ; Gaines, Helen E. ; Daniel Castracane, V.</creator><creatorcontrib>Johnson, Lisa G. ; Kraemer, Robert R. ; Haltom, Ron ; Kraemer, Ginger R. ; Gaines, Helen E. ; Daniel Castracane, V.</creatorcontrib><description>Objective: To determine the effects of hormone replacement therapy (HRT) drosterone (DHEA), DHEA sulfate (DHEAS), and cortisol (F) responses to treadmill exercise.
Design: Controlled clinical study.
Setting: Female volunteers in an academic research environment.
Patient(s): Sixteen healthy, postmenopausal women (7 were receiving HRT, 9 were not).
Intervention(s): Blood samples were taken, from an intravenous cathether before, during, and after 30 minutes of treadmill exercise following an overnight fast. A second session was conducted one month later for the same subjects using the same blood sampling protocol without exercise.
Main Outcome Measure(s): Serum DHEA, DHEAS, and F concentrations.
Result(s): The HRT and untreated DHEA area under the curve (AUC) for the exercise trials was significantly greater than that for the control trials. The untreated, but not the HRT, DHEAS AUC for the exercise trials was significantly greater than that for the control trials. The HRT and untreated F AUC for the exercise trials was significantly greater than that for the control trials. The AUC for the HRT exercise trials was significantly higher than the untreated exercise trials for DHEA and F, but not DHEAS.
Conclusion(s): Data suggest that treadmill exercise elevates DHEA, DHEAS, and F levels in postmenopausal women and that HRT enhances the DHEA and F responses.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/S0015-0282(97)00369-5</identifier><identifier>PMID: 9389812</identifier><identifier>CODEN: FESTAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>adrenal androgens ; Adrenocorticotropic Hormone - metabolism ; Biological and medical sciences ; cortisol ; Dehydroepiandrosterone - blood ; Dehydroepiandrosterone Sulfate - blood ; dehydroepiandrosterone-sulfate ; DHEA ; Estradiol - blood ; Estrogen Replacement Therapy ; exercise ; Exercise - physiology ; Female ; Follicle Stimulating Hormone - blood ; Fundamental and applied biological sciences. Psychology ; Hormone metabolism and regulation ; hormone replacement ; Humans ; Hydrocortisone - blood ; Kinetics ; Lactic Acid - blood ; Luteinizing Hormone - blood ; Mammalian female genital system ; Middle Aged ; Oxygen Consumption ; Plasma Volume ; Postmenopausal ; Postmenopause ; Vertebrates: reproduction</subject><ispartof>Fertility and sterility, 1997-11, Vol.68 (5), p.836-843</ispartof><rights>1997</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-1ae3334e6cfe98213261597744576962095d6a7aaade193755befa20a8ed9bc3</citedby><cites>FETCH-LOGICAL-c436t-1ae3334e6cfe98213261597744576962095d6a7aaade193755befa20a8ed9bc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0015-0282(97)00369-5$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2118346$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9389812$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Johnson, Lisa G.</creatorcontrib><creatorcontrib>Kraemer, Robert R.</creatorcontrib><creatorcontrib>Haltom, Ron</creatorcontrib><creatorcontrib>Kraemer, Ginger R.</creatorcontrib><creatorcontrib>Gaines, Helen E.</creatorcontrib><creatorcontrib>Daniel Castracane, V.</creatorcontrib><title>Effects of estrogen replacement therapy on dehydroepiandrosterone, dehydroepiandrosterone sulfate, and cortisol responses to exercise in postmenopausal women</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>Objective: To determine the effects of hormone replacement therapy (HRT) drosterone (DHEA), DHEA sulfate (DHEAS), and cortisol (F) responses to treadmill exercise.
Design: Controlled clinical study.
Setting: Female volunteers in an academic research environment.
Patient(s): Sixteen healthy, postmenopausal women (7 were receiving HRT, 9 were not).
Intervention(s): Blood samples were taken, from an intravenous cathether before, during, and after 30 minutes of treadmill exercise following an overnight fast. A second session was conducted one month later for the same subjects using the same blood sampling protocol without exercise.
Main Outcome Measure(s): Serum DHEA, DHEAS, and F concentrations.
Result(s): The HRT and untreated DHEA area under the curve (AUC) for the exercise trials was significantly greater than that for the control trials. The untreated, but not the HRT, DHEAS AUC for the exercise trials was significantly greater than that for the control trials. The HRT and untreated F AUC for the exercise trials was significantly greater than that for the control trials. The AUC for the HRT exercise trials was significantly higher than the untreated exercise trials for DHEA and F, but not DHEAS.
Conclusion(s): Data suggest that treadmill exercise elevates DHEA, DHEAS, and F levels in postmenopausal women and that HRT enhances the DHEA and F responses.</description><subject>adrenal androgens</subject><subject>Adrenocorticotropic Hormone - metabolism</subject><subject>Biological and medical sciences</subject><subject>cortisol</subject><subject>Dehydroepiandrosterone - blood</subject><subject>Dehydroepiandrosterone Sulfate - blood</subject><subject>dehydroepiandrosterone-sulfate</subject><subject>DHEA</subject><subject>Estradiol - blood</subject><subject>Estrogen Replacement Therapy</subject><subject>exercise</subject><subject>Exercise - physiology</subject><subject>Female</subject><subject>Follicle Stimulating Hormone - blood</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hormone metabolism and regulation</subject><subject>hormone replacement</subject><subject>Humans</subject><subject>Hydrocortisone - blood</subject><subject>Kinetics</subject><subject>Lactic Acid - blood</subject><subject>Luteinizing Hormone - blood</subject><subject>Mammalian female genital system</subject><subject>Middle Aged</subject><subject>Oxygen Consumption</subject><subject>Plasma Volume</subject><subject>Postmenopausal</subject><subject>Postmenopause</subject><subject>Vertebrates: reproduction</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUU2LFDEQDaKs4-pPWMhBRMHWfHSSzklkWT9gwYN7DzXpihvpSdqkW50f4381uzPMTTwVqfdeVeU9Qi44e8MZ12-_MsZVx8QgXlrzijGpbacekA1XSndKK_mQbE6Ux-RJrd8ZY5obcUbOrBzswMWG_LkKAf1SaQ4U61LyN0y04DyBxx2mhS63WGDe05zoiLf7sWScI6RW64IlJ3z9jz6t6xRgaXjrUp_LEmue2uw651Sx0iVT_I3Fx4o0Jjo3YduYZ1grTPRXbo-n5FGAqeKzYz0nNx-ubi4_dddfPn6-fH_d-V7qpeOAUsoetQ9oB8Gl0FxZY_peGW21YFaNGgwAjMitNEptMYBgMOBot16ekxeHsXPJP9Zmg9vF6nGaIGFeqzO27w3TQyOqA9G3b9aCwc0l7qDsHWfuLhV3n4q7s9xZ4-5TcarpLo4L1u0Ox5PqGEPDnx9xqB6mUCA1W040wfkge91o7w40bF78jFhc9RGTxzGWFqIbc_zPIX8BfBauOw</recordid><startdate>19971101</startdate><enddate>19971101</enddate><creator>Johnson, Lisa G.</creator><creator>Kraemer, Robert R.</creator><creator>Haltom, Ron</creator><creator>Kraemer, Ginger R.</creator><creator>Gaines, Helen E.</creator><creator>Daniel Castracane, V.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19971101</creationdate><title>Effects of estrogen replacement therapy on dehydroepiandrosterone, dehydroepiandrosterone sulfate, and cortisol responses to exercise in postmenopausal women</title><author>Johnson, Lisa G. ; Kraemer, Robert R. ; Haltom, Ron ; Kraemer, Ginger R. ; Gaines, Helen E. ; Daniel Castracane, V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c436t-1ae3334e6cfe98213261597744576962095d6a7aaade193755befa20a8ed9bc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>adrenal androgens</topic><topic>Adrenocorticotropic Hormone - metabolism</topic><topic>Biological and medical sciences</topic><topic>cortisol</topic><topic>Dehydroepiandrosterone - blood</topic><topic>Dehydroepiandrosterone Sulfate - blood</topic><topic>dehydroepiandrosterone-sulfate</topic><topic>DHEA</topic><topic>Estradiol - blood</topic><topic>Estrogen Replacement Therapy</topic><topic>exercise</topic><topic>Exercise - physiology</topic><topic>Female</topic><topic>Follicle Stimulating Hormone - blood</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hormone metabolism and regulation</topic><topic>hormone replacement</topic><topic>Humans</topic><topic>Hydrocortisone - blood</topic><topic>Kinetics</topic><topic>Lactic Acid - blood</topic><topic>Luteinizing Hormone - blood</topic><topic>Mammalian female genital system</topic><topic>Middle Aged</topic><topic>Oxygen Consumption</topic><topic>Plasma Volume</topic><topic>Postmenopausal</topic><topic>Postmenopause</topic><topic>Vertebrates: reproduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Johnson, Lisa G.</creatorcontrib><creatorcontrib>Kraemer, Robert R.</creatorcontrib><creatorcontrib>Haltom, Ron</creatorcontrib><creatorcontrib>Kraemer, Ginger R.</creatorcontrib><creatorcontrib>Gaines, Helen E.</creatorcontrib><creatorcontrib>Daniel Castracane, V.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Johnson, Lisa G.</au><au>Kraemer, Robert R.</au><au>Haltom, Ron</au><au>Kraemer, Ginger R.</au><au>Gaines, Helen E.</au><au>Daniel Castracane, V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of estrogen replacement therapy on dehydroepiandrosterone, dehydroepiandrosterone sulfate, and cortisol responses to exercise in postmenopausal women</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>1997-11-01</date><risdate>1997</risdate><volume>68</volume><issue>5</issue><spage>836</spage><epage>843</epage><pages>836-843</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>Objective: To determine the effects of hormone replacement therapy (HRT) drosterone (DHEA), DHEA sulfate (DHEAS), and cortisol (F) responses to treadmill exercise.
Design: Controlled clinical study.
Setting: Female volunteers in an academic research environment.
Patient(s): Sixteen healthy, postmenopausal women (7 were receiving HRT, 9 were not).
Intervention(s): Blood samples were taken, from an intravenous cathether before, during, and after 30 minutes of treadmill exercise following an overnight fast. A second session was conducted one month later for the same subjects using the same blood sampling protocol without exercise.
Main Outcome Measure(s): Serum DHEA, DHEAS, and F concentrations.
Result(s): The HRT and untreated DHEA area under the curve (AUC) for the exercise trials was significantly greater than that for the control trials. The untreated, but not the HRT, DHEAS AUC for the exercise trials was significantly greater than that for the control trials. The HRT and untreated F AUC for the exercise trials was significantly greater than that for the control trials. The AUC for the HRT exercise trials was significantly higher than the untreated exercise trials for DHEA and F, but not DHEAS.
Conclusion(s): Data suggest that treadmill exercise elevates DHEA, DHEAS, and F levels in postmenopausal women and that HRT enhances the DHEA and F responses.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>9389812</pmid><doi>10.1016/S0015-0282(97)00369-5</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0015-0282 |
| ispartof | Fertility and sterility, 1997-11, Vol.68 (5), p.836-843 |
| issn | 0015-0282 1556-5653 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79447068 |
| source | MEDLINE; Elsevier ScienceDirect Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | adrenal androgens Adrenocorticotropic Hormone - metabolism Biological and medical sciences cortisol Dehydroepiandrosterone - blood Dehydroepiandrosterone Sulfate - blood dehydroepiandrosterone-sulfate DHEA Estradiol - blood Estrogen Replacement Therapy exercise Exercise - physiology Female Follicle Stimulating Hormone - blood Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation hormone replacement Humans Hydrocortisone - blood Kinetics Lactic Acid - blood Luteinizing Hormone - blood Mammalian female genital system Middle Aged Oxygen Consumption Plasma Volume Postmenopausal Postmenopause Vertebrates: reproduction |
| title | Effects of estrogen replacement therapy on dehydroepiandrosterone, dehydroepiandrosterone sulfate, and cortisol responses to exercise in postmenopausal women |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T14%3A10%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20estrogen%20replacement%20therapy%20on%20dehydroepiandrosterone,%20dehydroepiandrosterone%20sulfate,%20and%20cortisol%20responses%20to%20exercise%20in%20postmenopausal%20women&rft.jtitle=Fertility%20and%20sterility&rft.au=Johnson,%20Lisa%20G.&rft.date=1997-11-01&rft.volume=68&rft.issue=5&rft.spage=836&rft.epage=843&rft.pages=836-843&rft.issn=0015-0282&rft.eissn=1556-5653&rft.coden=FESTAS&rft_id=info:doi/10.1016/S0015-0282(97)00369-5&rft_dat=%3Cproquest_cross%3E79447068%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79447068&rft_id=info:pmid/9389812&rft_els_id=S0015028297003695&rfr_iscdi=true |