Effect of several vasoactive agents on guanylate cyclase activity in isolated rat brain microvessels

We tested the ability of the following putative vasoactive agents to stimulate guanylate cyclase activity in isolated rat cerebral microvessels: angiotensin II, arginine vasopressin, atrial natriuretic peptide, bradykinin, carbachol and thrombin; at concentrations ranging between 10 −3 and 10 −9 M....

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Veröffentlicht in:	Neuroscience letters 1989-12, Vol.107 (1), p.273-278
Hauptverfasser:	Homayoun, Parvin, Lust, W.David, Harik, Sami I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin II Angiotensin II - pharmacology Animals Arginine vasopressin Arginine Vasopressin - pharmacology Atrial Natriuretic Factor - pharmacology Atrial natriuretic peptide Biological and medical sciences Blood Vessels - drug effects Blood Vessels - enzymology Blood Vessels - metabolism Blood-brain barrier Bradykinin Brain - blood supply Brain microvessel Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Cyclic GMP Cyclic GMP - metabolism Fundamental and applied biological sciences. Psychology Guanylate Cyclase - metabolism In Vitro Techniques Male Rats Rats, Inbred Strains Vertebrates: nervous system and sense organs
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