Premenopausal Ovariectomy‐Related Bone Loss: A Randomized, Double‐Blind, One‐Year Trial of Conjugated Estrogen or Medroxyprogesterone Acetate

The purpose of this study was to contrast the effects of conventional estrogen treatment with medroxyprogesterone on cancellous and cortical bone change in the first year following premenopausal ovariectomy. This 1‐year double‐blind randomized therapy trial was stratified by osteoporosis family hist...

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Veröffentlicht in:	Journal of bone and mineral research 1997-11, Vol.12 (11), p.1851-1863
Hauptverfasser:	Prior, Jerilynn C., Vigna, Yvette M., Wark, John D., Eyre, David R., Lentle, Brian C., Li, David K. B., Ebeling, Peter R., Atley, Lynne
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon Adult Alkaline Phosphatase - metabolism Biological and medical sciences Bone Density - drug effects Bone Resorption - drug therapy Bone Resorption - etiology Bones, joints and connective tissue. Antiinflammatory agents Calcium, Dietary - administration & dosage Double-Blind Method Estrogen Replacement Therapy Female Femur - diagnostic imaging Femur - drug effects Humans Medical sciences Medroxyprogesterone Acetate - therapeutic use Middle Aged Osteoporosis - etiology Osteoporosis - prevention & control Ovariectomy Pharmacology. Drug treatments Premenopause Progesterone Congeners - therapeutic use Thoracic Vertebrae - diagnostic imaging Thoracic Vertebrae - drug effects Weight Gain - drug effects
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