Developmental changes in NMDA receptor expression in the platyfish brain
We have examined the distribution of the N-methyl- d-aspartate (NMDA) receptor in the brain of a freshwater teleost using an antibody against the R1 subunit of the receptor (NMDAR1). The primary site of localization was the nucleus olfactoretinalis (NOR), a significant gonadotropin releasing hormone...
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| Veröffentlicht in: | Brain research 1997-10, Vol.771 (1), p.142-146 |
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| container_title | Brain research |
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| creator | Flynn, Katherine M Schreibman, Martin P Magliulo-Cepriano, Lucia |
| description | We have examined the distribution of the
N-methyl-
d-aspartate (NMDA) receptor in the brain of a freshwater teleost using an antibody against the R1 subunit of the receptor (NMDAR1). The primary site of localization was the nucleus olfactoretinalis (NOR), a significant gonadotropin releasing hormone (GnRH)-containing brain nucleus. The number of cells expressing NMDAR1 in this nucleus was dependent upon developmental stage, with pubescent and mature animals displaying significantly more stained cells than immature and senescent animals. This is the first reported observation of age- and maturity-related NMDA receptor association with GnRH-containing brain areas. |
| doi_str_mv | 10.1016/S0006-8993(97)00626-4 |
| format | Article |
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N-methyl-
d-aspartate (NMDA) receptor in the brain of a freshwater teleost using an antibody against the R1 subunit of the receptor (NMDAR1). The primary site of localization was the nucleus olfactoretinalis (NOR), a significant gonadotropin releasing hormone (GnRH)-containing brain nucleus. The number of cells expressing NMDAR1 in this nucleus was dependent upon developmental stage, with pubescent and mature animals displaying significantly more stained cells than immature and senescent animals. This is the first reported observation of age- and maturity-related NMDA receptor association with GnRH-containing brain areas.</description><subject>Aging</subject><subject>Aging - metabolism</subject><subject>Animals</subject><subject>Brain - growth & development</subject><subject>Brain - metabolism</subject><subject>Cyprinodontiformes - growth & development</subject><subject>Freshwater</subject><subject>Gene Expression Regulation, Developmental</subject><subject>Glutamate</subject><subject>GnRH</subject><subject>Gonadotropin-Releasing Hormone - metabolism</subject><subject>Hypothalamus</subject><subject>Life Sciences (General)</subject><subject>Organ Specificity</subject><subject>Puberty</subject><subject>Receptors, N-Methyl-D-Aspartate - analysis</subject><subject>Receptors, N-Methyl-D-Aspartate - biosynthesis</subject><subject>Space life sciences</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>CYI</sourceid><sourceid>EIF</sourceid><recordid>eNqFkLlOAzEQhi0EgnC8AUhbISgWfMVHhRC3xFEAteV4x8Ro413sDYK3xyERLZXH-v6ZsT-EDgg-IZiI02eMsaiV1uxIy-NSU1HzNTQiStJaUI7X0egvsoW2c34vV8Y03kSbmimGiRyh20v4hLbrZxAH21ZuauMb5CrE6vHh8rxK4KAfulTBV58g59DFBRumUPWtHb59yNNqkmyIu2jD2zbD3urcQa_XVy8Xt_X9083dxfl97TihQ0015bLhY-qlYlb5MVVeKQfSNV5p4Zkj0DBfPuOAUoYbNRHWOtAMM2BcsR10uJzbp-5jDnkws5AdtK2N0M2zkZozjrn-N0gEJVpwXoLjZdClLucE3vQpzGz6NgSbhWrzq9osPBotza9qs-g7WC2YT2bQ_HWt3Ba-v-TRZmvikLKhGPOCqNSi4LMlhmLrM0Ay2QWIDppQrA-m6cI_D_gBh3KVwA</recordid><startdate>19971010</startdate><enddate>19971010</enddate><creator>Flynn, Katherine M</creator><creator>Schreibman, Martin P</creator><creator>Magliulo-Cepriano, Lucia</creator><general>Elsevier B.V</general><scope>CYE</scope><scope>CYI</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>F1W</scope><scope>H95</scope><scope>L.G</scope><scope>7X8</scope></search><sort><creationdate>19971010</creationdate><title>Developmental changes in NMDA receptor expression in the platyfish brain</title><author>Flynn, Katherine M ; Schreibman, Martin P ; Magliulo-Cepriano, Lucia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c412t-29247d452f783a8f528f88ce7cdf896f3c1ed3f626ce2230d8b6aace9303e3483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Aging</topic><topic>Aging - metabolism</topic><topic>Animals</topic><topic>Brain - growth & development</topic><topic>Brain - metabolism</topic><topic>Cyprinodontiformes - growth & development</topic><topic>Freshwater</topic><topic>Gene Expression Regulation, Developmental</topic><topic>Glutamate</topic><topic>GnRH</topic><topic>Gonadotropin-Releasing Hormone - metabolism</topic><topic>Hypothalamus</topic><topic>Life Sciences (General)</topic><topic>Organ Specificity</topic><topic>Puberty</topic><topic>Receptors, N-Methyl-D-Aspartate - analysis</topic><topic>Receptors, N-Methyl-D-Aspartate - biosynthesis</topic><topic>Space life sciences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Flynn, Katherine M</creatorcontrib><creatorcontrib>Schreibman, Martin P</creatorcontrib><creatorcontrib>Magliulo-Cepriano, Lucia</creatorcontrib><collection>NASA Scientific and Technical Information</collection><collection>NASA Technical Reports Server</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Flynn, Katherine M</au><au>Schreibman, Martin P</au><au>Magliulo-Cepriano, Lucia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Developmental changes in NMDA receptor expression in the platyfish brain</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1997-10-10</date><risdate>1997</risdate><volume>771</volume><issue>1</issue><spage>142</spage><epage>146</epage><pages>142-146</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><abstract>We have examined the distribution of the
N-methyl-
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| fulltext | fulltext |
| identifier | ISSN: 0006-8993 |
| ispartof | Brain research, 1997-10, Vol.771 (1), p.142-146 |
| issn | 0006-8993 1872-6240 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals; NASA Technical Reports Server |
| subjects | Aging Aging - metabolism Animals Brain - growth & development Brain - metabolism Cyprinodontiformes - growth & development Freshwater Gene Expression Regulation, Developmental Glutamate GnRH Gonadotropin-Releasing Hormone - metabolism Hypothalamus Life Sciences (General) Organ Specificity Puberty Receptors, N-Methyl-D-Aspartate - analysis Receptors, N-Methyl-D-Aspartate - biosynthesis Space life sciences |
| title | Developmental changes in NMDA receptor expression in the platyfish brain |
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