Lesions of the SDN-POA inhibit sexual behavior of male wistar rats
Discrete bilateral lesions in the SDN-POA of sexually naive adult male rats were found to decrease the number of animals ejaculating and/or to increase latencies to the first mount, intromission and ejaculation. The deleterious effects of the lesions disappeared after 4 tests for sexual behavior but...
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| Veröffentlicht in: | Brain research bulletin 1989-12, Vol.23 (6), p.483-492 |
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| container_title | Brain research bulletin |
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| creator | De Jonge, F.H. Louwerse, A.L. Ooms, M.P. Evers, P. Endert, E. Van De Poll, N.E. |
| description | Discrete bilateral lesions in the SDN-POA of sexually naive adult male rats were found to decrease the number of animals ejaculating and/or to increase latencies to the first mount, intromission and ejaculation. The deleterious effects of the lesions disappeared after 4 tests for sexual behavior but were reinstated when the males were tested under suboptimal conditions i.e., when they were tested with a marginally receptive female or when they had only limited access to the stimulus female. It was subsequently shown that males with a bilaterally lesioned SDN-POA still showed an increase in plasma testosterone, LH and prolactin levels in response to sexual stimulation. Effects of the lesions on scent marking were not found. Together with previous data indicating that SDN-POA-lesions disrupt masculine sexual behavior in females, these data are taken as evidence that the SDN-POA plays a role in the regulation of masculine sexual behavior. The data further suggest that previously reported negative results of SDN-POA-lesions on masculine sexual behavior in male rats might be attributed to the use of sexually experienced instead of sexually inexperienced animals. |
| doi_str_mv | 10.1016/0361-9230(89)90194-9 |
| format | Article |
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The deleterious effects of the lesions disappeared after 4 tests for sexual behavior but were reinstated when the males were tested under suboptimal conditions i.e., when they were tested with a marginally receptive female or when they had only limited access to the stimulus female. It was subsequently shown that males with a bilaterally lesioned SDN-POA still showed an increase in plasma testosterone, LH and prolactin levels in response to sexual stimulation. Effects of the lesions on scent marking were not found. Together with previous data indicating that SDN-POA-lesions disrupt masculine sexual behavior in females, these data are taken as evidence that the SDN-POA plays a role in the regulation of masculine sexual behavior. The data further suggest that previously reported negative results of SDN-POA-lesions on masculine sexual behavior in male rats might be attributed to the use of sexually experienced instead of sexually inexperienced animals.</description><identifier>ISSN: 0361-9230</identifier><identifier>EISSN: 1873-2747</identifier><identifier>DOI: 10.1016/0361-9230(89)90194-9</identifier><identifier>PMID: 2611691</identifier><identifier>CODEN: BRBUDU</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Animals ; Behavioral psychophysiology ; Biological and medical sciences ; Fundamental and applied biological sciences. Psychology ; LH Prolactin ; Male ; Masculine sexual behavior ; Preoptic Area - physiology ; Psychology. Psychoanalysis. Psychiatry ; Psychology. Psychophysiology ; Rats ; Rats, Inbred Strains ; Scent marking ; SDN-POA-lesions ; Sexual Behavior, Animal - physiology ; Testosterone ; Testosterone - blood</subject><ispartof>Brain research bulletin, 1989-12, Vol.23 (6), p.483-492</ispartof><rights>1989</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-46e56425786d72618a67d16a79f02441bfc3d3ed5be62bc31bbe46694f2e7fda3</citedby><cites>FETCH-LOGICAL-c483t-46e56425786d72618a67d16a79f02441bfc3d3ed5be62bc31bbe46694f2e7fda3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0361-9230(89)90194-9$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6761361$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2611691$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>De Jonge, F.H.</creatorcontrib><creatorcontrib>Louwerse, A.L.</creatorcontrib><creatorcontrib>Ooms, M.P.</creatorcontrib><creatorcontrib>Evers, P.</creatorcontrib><creatorcontrib>Endert, E.</creatorcontrib><creatorcontrib>Van De Poll, N.E.</creatorcontrib><title>Lesions of the SDN-POA inhibit sexual behavior of male wistar rats</title><title>Brain research bulletin</title><addtitle>Brain Res Bull</addtitle><description>Discrete bilateral lesions in the SDN-POA of sexually naive adult male rats were found to decrease the number of animals ejaculating and/or to increase latencies to the first mount, intromission and ejaculation. The deleterious effects of the lesions disappeared after 4 tests for sexual behavior but were reinstated when the males were tested under suboptimal conditions i.e., when they were tested with a marginally receptive female or when they had only limited access to the stimulus female. It was subsequently shown that males with a bilaterally lesioned SDN-POA still showed an increase in plasma testosterone, LH and prolactin levels in response to sexual stimulation. Effects of the lesions on scent marking were not found. Together with previous data indicating that SDN-POA-lesions disrupt masculine sexual behavior in females, these data are taken as evidence that the SDN-POA plays a role in the regulation of masculine sexual behavior. The data further suggest that previously reported negative results of SDN-POA-lesions on masculine sexual behavior in male rats might be attributed to the use of sexually experienced instead of sexually inexperienced animals.</description><subject>Animals</subject><subject>Behavioral psychophysiology</subject><subject>Biological and medical sciences</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>LH Prolactin</subject><subject>Male</subject><subject>Masculine sexual behavior</subject><subject>Preoptic Area - physiology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychology. Psychophysiology</subject><subject>Rats</subject><subject>Rats, Inbred Strains</subject><subject>Scent marking</subject><subject>SDN-POA-lesions</subject><subject>Sexual Behavior, Animal - physiology</subject><subject>Testosterone</subject><subject>Testosterone - blood</subject><issn>0361-9230</issn><issn>1873-2747</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LxDAQhoMoun78A4UeRPRQzTRp0lyE9VtYVFDPIU2nbKTbatKu-u9t3WWPeprD-8w7w0PIPtBToCDOKBMQq4TR40ydKAqKx2qNjCCTLE4kl-tktEK2yHYIb5RSkaVik2wmAkAoGJGLCQbX1CFqyqidYvR89RA_PY4jV09d7too4FdnqijHqZm7xg_YzFQYfbrQGh9504ZdslGaKuDecu6Q15vrl8u7ePJ4e385nsSWZ6yNucBU8CSVmShkfz8zQhYgjFQlTTiHvLSsYFikOYoktwzyHLkQipcJyrIwbIccLXrfffPRYWj1zAWLVWVqbLqgpeKMUan-BSHllKUAPcgXoPVNCB5L_e7dzPhvDVQPjvUgUA8Cdab0r2M99B8s-7t8hsVqaSm1zw-XuQnWVKU3tXVhhQkpoK_tsfMFhr20uUOvg3VYWyycR9vqonF___ED76uVsQ</recordid><startdate>19891201</startdate><enddate>19891201</enddate><creator>De Jonge, F.H.</creator><creator>Louwerse, A.L.</creator><creator>Ooms, M.P.</creator><creator>Evers, P.</creator><creator>Endert, E.</creator><creator>Van De Poll, N.E.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19891201</creationdate><title>Lesions of the SDN-POA inhibit sexual behavior of male wistar rats</title><author>De Jonge, F.H. ; Louwerse, A.L. ; Ooms, M.P. ; Evers, P. ; Endert, E. ; Van De Poll, N.E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-46e56425786d72618a67d16a79f02441bfc3d3ed5be62bc31bbe46694f2e7fda3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Animals</topic><topic>Behavioral psychophysiology</topic><topic>Biological and medical sciences</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>LH Prolactin</topic><topic>Male</topic><topic>Masculine sexual behavior</topic><topic>Preoptic Area - physiology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychology. Psychophysiology</topic><topic>Rats</topic><topic>Rats, Inbred Strains</topic><topic>Scent marking</topic><topic>SDN-POA-lesions</topic><topic>Sexual Behavior, Animal - physiology</topic><topic>Testosterone</topic><topic>Testosterone - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>De Jonge, F.H.</creatorcontrib><creatorcontrib>Louwerse, A.L.</creatorcontrib><creatorcontrib>Ooms, M.P.</creatorcontrib><creatorcontrib>Evers, P.</creatorcontrib><creatorcontrib>Endert, E.</creatorcontrib><creatorcontrib>Van De Poll, N.E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>De Jonge, F.H.</au><au>Louwerse, A.L.</au><au>Ooms, M.P.</au><au>Evers, P.</au><au>Endert, E.</au><au>Van De Poll, N.E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lesions of the SDN-POA inhibit sexual behavior of male wistar rats</atitle><jtitle>Brain research bulletin</jtitle><addtitle>Brain Res Bull</addtitle><date>1989-12-01</date><risdate>1989</risdate><volume>23</volume><issue>6</issue><spage>483</spage><epage>492</epage><pages>483-492</pages><issn>0361-9230</issn><eissn>1873-2747</eissn><coden>BRBUDU</coden><abstract>Discrete bilateral lesions in the SDN-POA of sexually naive adult male rats were found to decrease the number of animals ejaculating and/or to increase latencies to the first mount, intromission and ejaculation. The deleterious effects of the lesions disappeared after 4 tests for sexual behavior but were reinstated when the males were tested under suboptimal conditions i.e., when they were tested with a marginally receptive female or when they had only limited access to the stimulus female. It was subsequently shown that males with a bilaterally lesioned SDN-POA still showed an increase in plasma testosterone, LH and prolactin levels in response to sexual stimulation. Effects of the lesions on scent marking were not found. Together with previous data indicating that SDN-POA-lesions disrupt masculine sexual behavior in females, these data are taken as evidence that the SDN-POA plays a role in the regulation of masculine sexual behavior. The data further suggest that previously reported negative results of SDN-POA-lesions on masculine sexual behavior in male rats might be attributed to the use of sexually experienced instead of sexually inexperienced animals.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>2611691</pmid><doi>10.1016/0361-9230(89)90194-9</doi><tpages>10</tpages></addata></record> |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals Behavioral psychophysiology Biological and medical sciences Fundamental and applied biological sciences. Psychology LH Prolactin Male Masculine sexual behavior Preoptic Area - physiology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Inbred Strains Scent marking SDN-POA-lesions Sexual Behavior, Animal - physiology Testosterone Testosterone - blood |
| title | Lesions of the SDN-POA inhibit sexual behavior of male wistar rats |
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