A role for FGF-8 in the dorsoventral patterning of the zebrafish gastrula

Signals released from Spemann's organizer, together with ventralizing factors such as BMPs, are necessary to pattern the dorsoventral axis of the vertebrate embryo. We report that a member of the FGF family, fgf-8, not secreted by the axial mesoderm but expressed in a dorsoventral gradient at t...

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Veröffentlicht in:	Development (Cambridge) 1997-11, Vol.124 (21), p.4253-4264
Hauptverfasser:	Fürthauer, M, Thisse, C, Thisse, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Blastocyst - physiology Body Patterning - genetics Bone Morphogenetic Protein 2 Bone Morphogenetic Protein 4 Bone Morphogenetic Proteins - genetics Bone Morphogenetic Proteins - metabolism Cloning, Molecular Danio rerio Embryo, Nonmammalian Embryonic Induction - genetics Fibroblast Growth Factor 8 Fibroblast Growth Factors Freshwater Gastrula - physiology Gene Expression Regulation, Developmental Growth Substances - physiology Mesencephalon - embryology Molecular Sequence Data Sequence Analysis, DNA Sequence Homology, Amino Acid Transcription, Genetic Transforming Growth Factor beta Zebrafish - embryology Zebrafish - genetics Zebrafish Proteins
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