The pacemaker current I(f) in single human atrial myocytes and the effect of beta-adrenoceptor and A1-adenosine receptor stimulation

1. We used single human atrial myocytes to study I(f) occurrence, properties and pharmacological modulation. Cells were obtained by chunk enzymatic digestion from samples of right atrial appendages of patients undergoing corrective cardiac surgery. 2. Patch-clamped cells in the whole-cell configurat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of pharmacology 1997-11, Vol.122 (5), p.963-969
Hauptverfasser:	Porciatti, F, Pelzmann, B, Cerbai, E, Schaffer, P, Pino, R, Bernhart, E, Koidl, B, Mugelli, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - analogs & derivatives Adenosine - pharmacology Adrenergic beta-Agonists - pharmacology Aged Female Heart - drug effects Heart - physiology Heart Atria - cytology Heart Atria - drug effects Humans In Vitro Techniques Isoproterenol - pharmacology Male Membrane Potentials - drug effects Middle Aged Patch-Clamp Techniques Purinergic P1 Receptor Agonists Receptors, Purinergic P1 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!