Evaluation of protection by two endotoxin-neutralizing IgM monoclonal antibodies in different peritonitis models

Two anti-core glycolipid (CGL) IgM monoclonal antibodies (mAbs 8-2 and 26-20), previously shown to display cross-reactivity with heterologous lipopolysaccharide (LPS) in vitro and to provide cross-protectivity against endotoxin challenge in vivo, were evaluated for their potential to protect mice ag...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 1997-10, Vol.40 (4), p.567-572
Hauptverfasser:	HUSTINX, W. N. M, BENAISSA-TROUW, B. J, HARMSEN, T, KLEIN, S, VERHOEF, J, HOEPELMAN, A. I. M, KRAAIJEVELD, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antibodies, Monoclonal - therapeutic use Bacterial Infections - prevention & control Biological and medical sciences Endotoxins - immunology Female Glycolipids - immunology Immunoglobulin M - therapeutic use Medical sciences Mice Mice, Inbred BALB C Peritonitis - prevention & control Pharmacology. Drug treatments
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