Reversibility of the ionomycin promoted synaptosomal hydrogen peroxide production

We previously reported on the release of hydrogen peroxide from guinea pig cerebral cortex synaptosomes (13). An important finding was that in glutathione depleted synaptosomes a linear release of hydrogen peroxide is rapidly induced on addition of the Ca ++-ionophore ionomycin (in the presence of C...

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Veröffentlicht in:	Biochemical and biophysical research communications 1989-12, Vol.165 (3), p.1104-1109
Hauptverfasser:	Zoccarato, Franco, Deana, Renzo, Alexandre, Adolfo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Calcium - metabolism Cell physiology Cerebral Cortex - ultrastructure cortex Dinitrochlorobenzene - pharmacology Fundamental and applied biological sciences. Psychology gamma-Aminobutyric Acid - metabolism Glutathione - metabolism Guinea Pigs Hydrogen Peroxide - metabolism ionomycin Ionomycin - pharmacology Kinetics Membrane and intracellular transports Molecular and cellular biology Serum Albumin, Bovine - pharmacology synaptosomes Synaptosomes - drug effects Synaptosomes - metabolism
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