Evaluation of Excised Loach Skin for Studies on Transdermal Permeation of Drugs in Vitro

Transdermal permeation of drug across the excised skin of Asian pond loach (Misgurnus anguillicaudatus CANTOR) was studied in vitro. Ten kinds of drugs, D-glucose, L-glucose, sucrose, salicylic acid, cefazolin, urea, antipyrine, naphazoline, propranolol and enviomycin were permeated through the exci...

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Veröffentlicht in:	YAKUGAKU ZASSHI 1989/09/25, Vol.109(9), pp.656-661
Hauptverfasser:	WATANABE, Yoshiteru, HONGO, Shuji, MATSUMOTO, Mitsuo
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Animals Cypriniformes drug concentration drug permeability Hydrogen-Ion Concentration In Vitro Techniques loach skin Misgurnus anguillicaudatus Molecular Weight pH effect Pharmacokinetics Skin - metabolism Skin Absorption skin permeation test Skin Temperature transdermal flux
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