Clinical Significance of Intraoperative Cultures of Aneurysm Walls and Contents in Elective Abdominal Aortic Aneurysmectomy

To investigate the clinical significance of intraoperative cultures in elective abdominal aortic aneurysmectomy, we cultured the aneurysmal wall and contents in 90 patients undergoing vascular graft surgery. Prosthetic graft infection was documented in 1 out of 62 patients with negative cultures and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:European journal of epidemiology 1989-12, Vol.5 (4), p.521-525
Hauptverfasser: Brandimarte, C., Santini, C., Venditti, M., Baiocchi, P., Serra, P., Gallo, P., d'Amati, G., Rizzo, L., Speziale, F., Fiorani, P.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 525
container_issue 4
container_start_page 521
container_title European journal of epidemiology
container_volume 5
creator Brandimarte, C.
Santini, C.
Venditti, M.
Baiocchi, P.
Serra, P.
Gallo, P.
d'Amati, G.
Rizzo, L.
Speziale, F.
Fiorani, P.
description To investigate the clinical significance of intraoperative cultures in elective abdominal aortic aneurysmectomy, we cultured the aneurysmal wall and contents in 90 patients undergoing vascular graft surgery. Prosthetic graft infection was documented in 1 out of 62 patients with negative cultures and in none of 28 patients with positive cultures (${\rm x}^{2}=0.4$, p > 0.1). Bacterial growth was seen in neither of 2 inflammatory aneurysms, 3 of 14 atherosclerotic aneurysms and 2 of 5 aneurysms without specific features. A retrospective analysis of patients' charts aimed at finding possible risk factors failed to identify any correlation between results of cultures and length of hospitalization before surgery, time interval between angiography and surgery, route of angiography procedure or minutes of surgery before sample collection. We conclude that positive cultures may not imply clinical infection at the time of surgery and that prolonged post-operative organism-specific antibiotic therapy does not appear necessary to prevent graft contamination in patients undergoing elective abdominal aortic aneurysmectomy.
doi_str_mv 10.1007/BF00140150
format Article
fullrecord <record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_79417879</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>3521439</jstor_id><sourcerecordid>3521439</sourcerecordid><originalsourceid>FETCH-LOGICAL-c334t-321672ed505d266f549cd652ea18e610bb7c02d1b6f4654a483ac2a84349eaa63</originalsourceid><addsrcrecordid>eNqFkc9LHDEYhkOx6Gp76blCTh6Eab_8njluB62C4MGWHodMJlMimWRNMsLSf97RXbZHT98Hz_O-lxehLwS-EQD1_cc1AOFABHxAKyIUqxSt-RFaAWtYRZsGTtBpzo8AUEMjjtExlSBJTVboX-tdcEZ7_OD-BjcubzAWxxHfhpJ03Niki3u2uJ19mZPNr2gd7Jy2ecJ_tPcZ6zDgNoZiQ8nYBXzlrXnLrPshTi4s5euYijOH4MLjtP2EPo7aZ_t5f8_Q7-urX-1NdXf_87Zd31WGMV4qRolU1A4CxEClHAVvzCAFtZrUVhLoe2WADqSXI5eCa14zbaiuOeON1VqyM3Sx692k-DTbXLrJZWO918HGOXeq4UTVqnlXJIJzqggs4uVONCnmnOzYbZKbdNp2BLrXSbr_kyzy-b517ic7HNT9Bgv_uuOPucR0wExQwpf9XgCbL5A9</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15442710</pqid></control><display><type>article</type><title>Clinical Significance of Intraoperative Cultures of Aneurysm Walls and Contents in Elective Abdominal Aortic Aneurysmectomy</title><source>MEDLINE</source><source>JSTOR Archive Collection A-Z Listing</source><source>SpringerLink Journals - AutoHoldings</source><creator>Brandimarte, C. ; Santini, C. ; Venditti, M. ; Baiocchi, P. ; Serra, P. ; Gallo, P. ; d'Amati, G. ; Rizzo, L. ; Speziale, F. ; Fiorani, P.</creator><creatorcontrib>Brandimarte, C. ; Santini, C. ; Venditti, M. ; Baiocchi, P. ; Serra, P. ; Gallo, P. ; d'Amati, G. ; Rizzo, L. ; Speziale, F. ; Fiorani, P.</creatorcontrib><description>To investigate the clinical significance of intraoperative cultures in elective abdominal aortic aneurysmectomy, we cultured the aneurysmal wall and contents in 90 patients undergoing vascular graft surgery. Prosthetic graft infection was documented in 1 out of 62 patients with negative cultures and in none of 28 patients with positive cultures (${\rm x}^{2}=0.4$, p &gt; 0.1). Bacterial growth was seen in neither of 2 inflammatory aneurysms, 3 of 14 atherosclerotic aneurysms and 2 of 5 aneurysms without specific features. A retrospective analysis of patients' charts aimed at finding possible risk factors failed to identify any correlation between results of cultures and length of hospitalization before surgery, time interval between angiography and surgery, route of angiography procedure or minutes of surgery before sample collection. We conclude that positive cultures may not imply clinical infection at the time of surgery and that prolonged post-operative organism-specific antibiotic therapy does not appear necessary to prevent graft contamination in patients undergoing elective abdominal aortic aneurysmectomy.</description><identifier>ISSN: 0393-2990</identifier><identifier>ISSN: 0392-2990</identifier><identifier>EISSN: 1573-7284</identifier><identifier>DOI: 10.1007/BF00140150</identifier><identifier>PMID: 2606181</identifier><language>eng</language><publisher>Netherlands: Kluwer Academic Publishers</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Aneurysms ; Angiography ; Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Aorta, Abdominal - microbiology ; Aorta, Abdominal - surgery ; Aortic Aneurysm - microbiology ; Aortic Aneurysm - surgery ; Blood Vessel Prosthesis ; Equipment Contamination ; Female ; Humans ; Infections ; Intraoperative Period ; Male ; Middle Aged ; Ruptured aneurysm ; Staphylococcal Infections - diagnosis ; Staphylococcal Infections - drug therapy ; Staphylococcal Infections - prevention &amp; control ; Staphylococcus ; Staphylococcus - isolation &amp; purification ; Surgical specialties ; Thrombosis ; Tissue grafting ; Vascular grafting</subject><ispartof>European journal of epidemiology, 1989-12, Vol.5 (4), p.521-525</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c334t-321672ed505d266f549cd652ea18e610bb7c02d1b6f4654a483ac2a84349eaa63</citedby><cites>FETCH-LOGICAL-c334t-321672ed505d266f549cd652ea18e610bb7c02d1b6f4654a483ac2a84349eaa63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/3521439$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/3521439$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2606181$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brandimarte, C.</creatorcontrib><creatorcontrib>Santini, C.</creatorcontrib><creatorcontrib>Venditti, M.</creatorcontrib><creatorcontrib>Baiocchi, P.</creatorcontrib><creatorcontrib>Serra, P.</creatorcontrib><creatorcontrib>Gallo, P.</creatorcontrib><creatorcontrib>d'Amati, G.</creatorcontrib><creatorcontrib>Rizzo, L.</creatorcontrib><creatorcontrib>Speziale, F.</creatorcontrib><creatorcontrib>Fiorani, P.</creatorcontrib><title>Clinical Significance of Intraoperative Cultures of Aneurysm Walls and Contents in Elective Abdominal Aortic Aneurysmectomy</title><title>European journal of epidemiology</title><addtitle>Eur J Epidemiol</addtitle><description>To investigate the clinical significance of intraoperative cultures in elective abdominal aortic aneurysmectomy, we cultured the aneurysmal wall and contents in 90 patients undergoing vascular graft surgery. Prosthetic graft infection was documented in 1 out of 62 patients with negative cultures and in none of 28 patients with positive cultures (${\rm x}^{2}=0.4$, p &gt; 0.1). Bacterial growth was seen in neither of 2 inflammatory aneurysms, 3 of 14 atherosclerotic aneurysms and 2 of 5 aneurysms without specific features. A retrospective analysis of patients' charts aimed at finding possible risk factors failed to identify any correlation between results of cultures and length of hospitalization before surgery, time interval between angiography and surgery, route of angiography procedure or minutes of surgery before sample collection. We conclude that positive cultures may not imply clinical infection at the time of surgery and that prolonged post-operative organism-specific antibiotic therapy does not appear necessary to prevent graft contamination in patients undergoing elective abdominal aortic aneurysmectomy.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aneurysms</subject><subject>Angiography</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Aorta, Abdominal - microbiology</subject><subject>Aorta, Abdominal - surgery</subject><subject>Aortic Aneurysm - microbiology</subject><subject>Aortic Aneurysm - surgery</subject><subject>Blood Vessel Prosthesis</subject><subject>Equipment Contamination</subject><subject>Female</subject><subject>Humans</subject><subject>Infections</subject><subject>Intraoperative Period</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Ruptured aneurysm</subject><subject>Staphylococcal Infections - diagnosis</subject><subject>Staphylococcal Infections - drug therapy</subject><subject>Staphylococcal Infections - prevention &amp; control</subject><subject>Staphylococcus</subject><subject>Staphylococcus - isolation &amp; purification</subject><subject>Surgical specialties</subject><subject>Thrombosis</subject><subject>Tissue grafting</subject><subject>Vascular grafting</subject><issn>0393-2990</issn><issn>0392-2990</issn><issn>1573-7284</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc9LHDEYhkOx6Gp76blCTh6Eab_8njluB62C4MGWHodMJlMimWRNMsLSf97RXbZHT98Hz_O-lxehLwS-EQD1_cc1AOFABHxAKyIUqxSt-RFaAWtYRZsGTtBpzo8AUEMjjtExlSBJTVboX-tdcEZ7_OD-BjcubzAWxxHfhpJ03Niki3u2uJ19mZPNr2gd7Jy2ecJ_tPcZ6zDgNoZiQ8nYBXzlrXnLrPshTi4s5euYijOH4MLjtP2EPo7aZ_t5f8_Q7-urX-1NdXf_87Zd31WGMV4qRolU1A4CxEClHAVvzCAFtZrUVhLoe2WADqSXI5eCa14zbaiuOeON1VqyM3Sx692k-DTbXLrJZWO918HGOXeq4UTVqnlXJIJzqggs4uVONCnmnOzYbZKbdNp2BLrXSbr_kyzy-b517ic7HNT9Bgv_uuOPucR0wExQwpf9XgCbL5A9</recordid><startdate>19891201</startdate><enddate>19891201</enddate><creator>Brandimarte, C.</creator><creator>Santini, C.</creator><creator>Venditti, M.</creator><creator>Baiocchi, P.</creator><creator>Serra, P.</creator><creator>Gallo, P.</creator><creator>d'Amati, G.</creator><creator>Rizzo, L.</creator><creator>Speziale, F.</creator><creator>Fiorani, P.</creator><general>Kluwer Academic Publishers</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>19891201</creationdate><title>Clinical Significance of Intraoperative Cultures of Aneurysm Walls and Contents in Elective Abdominal Aortic Aneurysmectomy</title><author>Brandimarte, C. ; Santini, C. ; Venditti, M. ; Baiocchi, P. ; Serra, P. ; Gallo, P. ; d'Amati, G. ; Rizzo, L. ; Speziale, F. ; Fiorani, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c334t-321672ed505d266f549cd652ea18e610bb7c02d1b6f4654a483ac2a84349eaa63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aneurysms</topic><topic>Angiography</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibiotics</topic><topic>Aorta, Abdominal - microbiology</topic><topic>Aorta, Abdominal - surgery</topic><topic>Aortic Aneurysm - microbiology</topic><topic>Aortic Aneurysm - surgery</topic><topic>Blood Vessel Prosthesis</topic><topic>Equipment Contamination</topic><topic>Female</topic><topic>Humans</topic><topic>Infections</topic><topic>Intraoperative Period</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Ruptured aneurysm</topic><topic>Staphylococcal Infections - diagnosis</topic><topic>Staphylococcal Infections - drug therapy</topic><topic>Staphylococcal Infections - prevention &amp; control</topic><topic>Staphylococcus</topic><topic>Staphylococcus - isolation &amp; purification</topic><topic>Surgical specialties</topic><topic>Thrombosis</topic><topic>Tissue grafting</topic><topic>Vascular grafting</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brandimarte, C.</creatorcontrib><creatorcontrib>Santini, C.</creatorcontrib><creatorcontrib>Venditti, M.</creatorcontrib><creatorcontrib>Baiocchi, P.</creatorcontrib><creatorcontrib>Serra, P.</creatorcontrib><creatorcontrib>Gallo, P.</creatorcontrib><creatorcontrib>d'Amati, G.</creatorcontrib><creatorcontrib>Rizzo, L.</creatorcontrib><creatorcontrib>Speziale, F.</creatorcontrib><creatorcontrib>Fiorani, P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brandimarte, C.</au><au>Santini, C.</au><au>Venditti, M.</au><au>Baiocchi, P.</au><au>Serra, P.</au><au>Gallo, P.</au><au>d'Amati, G.</au><au>Rizzo, L.</au><au>Speziale, F.</au><au>Fiorani, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Significance of Intraoperative Cultures of Aneurysm Walls and Contents in Elective Abdominal Aortic Aneurysmectomy</atitle><jtitle>European journal of epidemiology</jtitle><addtitle>Eur J Epidemiol</addtitle><date>1989-12-01</date><risdate>1989</risdate><volume>5</volume><issue>4</issue><spage>521</spage><epage>525</epage><pages>521-525</pages><issn>0393-2990</issn><issn>0392-2990</issn><eissn>1573-7284</eissn><abstract>To investigate the clinical significance of intraoperative cultures in elective abdominal aortic aneurysmectomy, we cultured the aneurysmal wall and contents in 90 patients undergoing vascular graft surgery. Prosthetic graft infection was documented in 1 out of 62 patients with negative cultures and in none of 28 patients with positive cultures (${\rm x}^{2}=0.4$, p &gt; 0.1). Bacterial growth was seen in neither of 2 inflammatory aneurysms, 3 of 14 atherosclerotic aneurysms and 2 of 5 aneurysms without specific features. A retrospective analysis of patients' charts aimed at finding possible risk factors failed to identify any correlation between results of cultures and length of hospitalization before surgery, time interval between angiography and surgery, route of angiography procedure or minutes of surgery before sample collection. We conclude that positive cultures may not imply clinical infection at the time of surgery and that prolonged post-operative organism-specific antibiotic therapy does not appear necessary to prevent graft contamination in patients undergoing elective abdominal aortic aneurysmectomy.</abstract><cop>Netherlands</cop><pub>Kluwer Academic Publishers</pub><pmid>2606181</pmid><doi>10.1007/BF00140150</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0393-2990
ispartof European journal of epidemiology, 1989-12, Vol.5 (4), p.521-525
issn 0393-2990
0392-2990
1573-7284
language eng
recordid cdi_proquest_miscellaneous_79417879
source MEDLINE; JSTOR Archive Collection A-Z Listing; SpringerLink Journals - AutoHoldings
subjects Adult
Aged
Aged, 80 and over
Aneurysms
Angiography
Anti-Bacterial Agents - therapeutic use
Antibiotics
Aorta, Abdominal - microbiology
Aorta, Abdominal - surgery
Aortic Aneurysm - microbiology
Aortic Aneurysm - surgery
Blood Vessel Prosthesis
Equipment Contamination
Female
Humans
Infections
Intraoperative Period
Male
Middle Aged
Ruptured aneurysm
Staphylococcal Infections - diagnosis
Staphylococcal Infections - drug therapy
Staphylococcal Infections - prevention & control
Staphylococcus
Staphylococcus - isolation & purification
Surgical specialties
Thrombosis
Tissue grafting
Vascular grafting
title Clinical Significance of Intraoperative Cultures of Aneurysm Walls and Contents in Elective Abdominal Aortic Aneurysmectomy
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T21%3A57%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20Significance%20of%20Intraoperative%20Cultures%20of%20Aneurysm%20Walls%20and%20Contents%20in%20Elective%20Abdominal%20Aortic%20Aneurysmectomy&rft.jtitle=European%20journal%20of%20epidemiology&rft.au=Brandimarte,%20C.&rft.date=1989-12-01&rft.volume=5&rft.issue=4&rft.spage=521&rft.epage=525&rft.pages=521-525&rft.issn=0393-2990&rft.eissn=1573-7284&rft_id=info:doi/10.1007/BF00140150&rft_dat=%3Cjstor_proqu%3E3521439%3C/jstor_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15442710&rft_id=info:pmid/2606181&rft_jstor_id=3521439&rfr_iscdi=true