Inhalation anaesthetics block accommodation of pyramidal cell discharge in the rat hippocampus

The effects of the three inhalation anaesthetics enflurane, isoflurane and halothane were tested in vitro on accommodation of rat CA1 neurones. At near clinical concentrations (approximately 2.5%) the anaesthetics slightly depressed antidromic field potential responses. At the same concentrations th...

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Veröffentlicht in:	British journal of anaesthesia : BJA 1989-11, Vol.63 (5), p.581-586
Hauptverfasser:	SOUTHAN, A. P, WANN, K. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Calcium Channels - drug effects Drug toxicity and drugs side effects treatment Enflurane - pharmacology Evoked Potentials - drug effects Halothane - pharmacology Hippocampus - physiology In Vitro Techniques Isoflurane - pharmacology Medical sciences Neurons - drug effects Pharmacology. Drug treatments Propranolol - pharmacology Pyramidal Tracts - physiology Rats Sensory Thresholds - drug effects Toxicity: nervous system and muscle
Online-Zugang:	Volltext
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