The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition

The structural changes of Alzheimer's disease (AD) include a widespread alteration of neuronal cell processes in addition to senile plaques and neurofibrillary tangles. Since the antigenic characteristics of these abnormal neurites are similar to those of the abnormal neurites associated with t...

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Veröffentlicht in:	Annals of neurology 1989-12, Vol.26 (6), p.771-778
Hauptverfasser:	Tabaton, Massimo, Mandybur, Thaddeus I., Perry, George, Onorato, Michelle, Autilio-Gambetti, Lucila, Gambetti, Pierluigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Alzheimer Disease - metabolism Alzheimer Disease - pathology Amyloid - metabolism Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Humans Immunohistochemistry Intermediate Filament Proteins - metabolism Medical sciences Microtubule-Associated Proteins - metabolism Neurofibrils - pathology Neurofilament Proteins Neurology Subacute Sclerosing Panencephalitis - metabolism Subacute Sclerosing Panencephalitis - pathology tau Proteins Ubiquitins - metabolism
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