Characterization of rat spinal cord receptors to FLFQPQRFamide, a mammalian morphine modulating peptide: a binding study

An in vitro binding assay, using 125I-YLFQPQRFamide, a newly synthetized iodinated analog of FLFQPQRFamide, in which Phe 1 (F) has been substituted by a Tyr (Y), was developed to demonstrate and characterize putative binding sites of this brain morphine modulating peptide. This radioligand bound in...

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Veröffentlicht in:	Brain research 1989-10, Vol.500 (1), p.169-176
Hauptverfasser:	Allard, M., Geoffre, S., Legendre, P., Vincent, J.D., Simonnet, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Binding site Binding, Competitive Biological and medical sciences Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors FLFQPQRFamide FMRFamide Fundamental and applied biological sciences. Psychology In Vitro Techniques Male Molecular Sequence Data Morphine Neuropeptides - metabolism Oligopeptides - metabolism Rats Rats, Inbred Strains Receptors, Cell Surface - metabolism Spinal cord Spinal Cord - metabolism Vertebrates: nervous system and sense organs
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