Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase

Both vanadate and hydrogen peroxide (H2O2) are known to have insulin-mimetic effects. We previously reported that the mixture of vanadate plus H2O2 results in the generation of a peroxide(s) of vanadate, which strongly enhances IGF-II binding to rat adipocytes (Kadota et al., 1987b). We now report t...

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Veröffentlicht in:Biochemistry (Easton) 1989-10, Vol.28 (22), p.8864-8871
Hauptverfasser: Fantus, I. George, Kadota, Satoru, Deragon, Guy, Foster, Barbara, Posner, Barry I
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Sprache:eng
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