Parasite-driven in vitro human lymphocyte cytotoxicity against autologous infected macrophages from mucosal leishmaniasis

Parasite-specific cytotoxicity in human leishmaniasis was evaluated in an autologous system. PBL from cutaneous leishmaniasis (CL) or mucosal leishmaniasis (ML) patients were exposed to Leishmania amazonensis-infected autologous macrophages for 7 days and then used as effector cells in a cytotoxic a...

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Veröffentlicht in:	The Journal of immunology (1950) 1997-11, Vol.159 (9), p.4467-4473
Hauptverfasser:	Brodskyn, CI, Barral, A, Boaventura, V, Carvalho, E, Barral-Netto, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Cytotoxicity, Immunologic Humans Leishmania - immunology Leishmania - parasitology Leishmania amazonensis Leishmaniasis, Mucocutaneous - immunology Leishmaniasis, Mucocutaneous - parasitology Macrophages - immunology Macrophages - parasitology
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