Effects of Pinacidil on Myocardial Blood Flow and Infarct Size After Acute Left Anterior Descending Coronary Artery Occlusion and Reperfusion in Awake Dogs With and Without a Coexisting Left Circumflex Coronary Artery Stenosis

To determine whether partial stenosis of a second major coronary artery promoted vasodilator-induced coronary steal and increased infarct size after acute coronary artery occlusion, we produced acute myocardial infarction by 4-h left anterior descending coronary artery occlusion and 20-h reperfusion...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1989-11, Vol.14 (5), p.747-755
Hauptverfasser:	Sakamoto, Susumu, Liang, Chang-seng, Stone, Charles K, Hood, William B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure - drug effects Cardiac Output - drug effects Coronary Circulation - drug effects Dogs Guanidines - pharmacology Heart Rate - drug effects Myocardial Infarction - physiopathology Myocardial Reperfusion Pinacidil Vasodilator Agents - pharmacology
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