Concentration of cefuroxime in middle ear effusion of children with acute otitis media

Antibiotic concentrations in serum and middle ear effusion are important in determining therapeutic success in acute otitis media. For beta-lactams the most relevant pharmacokinetic index for clinical efficacy is the time for which serum concentrations exceed the minimum inhibitory concentration (MI...

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Veröffentlicht in:	The Pediatric infectious disease journal 1997-10, Vol.16 (10), p.959-962
Hauptverfasser:	THORODDSEN, E, MARR, C, EFTHYMIOPOULOS, C, THORARINSSON, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Administration, Oral Bacterial diseases Biological and medical sciences Cefuroxime - metabolism Cefuroxime - pharmacokinetics Cefuroxime - therapeutic use Cephalosporins - metabolism Cephalosporins - pharmacokinetics Cephalosporins - therapeutic use Child, Preschool Ent and stomatologic bacterial diseases Human bacterial diseases Humans Infant Infectious diseases Medical sciences Microbial Sensitivity Tests Otitis Media with Effusion - drug therapy Otitis Media with Effusion - metabolism
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