Stimulation of cellular alkaline phosphatase activity and its messenger RNA level in a human osteosarcoma cell line by 1,25-dihydroxyvitamin D3

1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) significantly stimulated cellular alkaline phosphatase activity in a human osteoblastic osteosarcoma cell line (TE-85 cells) in serum-free medium with 0.1% bovine serum albumin as the hormone carrier in a dose- and a time-dependent manner. The extent of the max...

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Veröffentlicht in:	Archives of biochemistry and biophysics 1989-12, Vol.275 (2), p.363-370
Hauptverfasser:	KYEYUNE-NYOMBI, E, WILLIAM LAU, K.-H, BAYLINK, D. J, STRONG, D. D
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - genetics Alkaline Phosphatase - metabolism Analytical, structural and metabolic biochemistry Biological and medical sciences Calcitriol - pharmacology Cell Division - drug effects Cell Line Culture Media DNA, Neoplasm - drug effects Enzymes and enzyme inhibitors Fundamental and applied biological sciences. Psychology Humans Hydrolases Kinetics Osteosarcoma RNA, Messenger - genetics Tumor Cells, Cultured - drug effects Tumor Cells, Cultured - enzymology
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