Pathophysiology of Premature Skin Aging Induced by Ultraviolet Light

Ultraviolet irradiation from the sun has deleterious effects in human skin, including sunburn, immune suppression, 1 cancer, and premature aging (photoaging). Sunburn and immune suppression occur acutely in response to excessive exposure to the sun, whereas skin cancer and photoaging result from acc...

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Veröffentlicht in:	The New England journal of medicine 1997-11, Vol.337 (20), p.1419-1429
Hauptverfasser:	Fisher, Gary J, Wang, ZengQuan, Datta, Subhash C, Varani, James, Kang, Sewon, Voorhees, John J
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Cutaneous Adult Air. Soil. Water. Waste. Feeding Biological and medical sciences Collagen - radiation effects Environment. Living conditions Female Humans Male Medical sciences Metalloendopeptidases - analysis Metalloendopeptidases - drug effects Metalloendopeptidases - metabolism Metalloendopeptidases - radiation effects Middle Aged Public health. Hygiene Public health. Hygiene-occupational medicine Skin - enzymology Skin - physiopathology Skin - radiation effects Skin Aging - pathology Skin Aging - physiology Tretinoin - pharmacology Ultraviolet Rays - adverse effects
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