Genomic imprinting in the rat: Linkage of Igf2 and H19 genes and opposite parental allele-specific expression during embryogenesis

Igf2 and H19 are closely linked imprinted genes in both mice and humans that are expressed from opposite parental alleles. In this study we demonstrate that these two genes are also closely linked in the rat, with the H19 gene mapping to within 145 kb of Igf2 on rat chromosome 1. We identified polym...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1997-10, Vol.45 (2), p.416-420
Hauptverfasser:	OVERALL, M, BAKKER, M, SPENCER, J, PARKER, N, SMITH, P, DZIADEK, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Base Sequence Biological and medical sciences Classical genetics, quantitative genetics, hybrids Crosses, Genetic DNA Primers - genetics Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental Genetic Linkage Genetics of eukaryotes. Biological and molecular evolution Genomic Imprinting Humans Insulin-Like Growth Factor II - genetics Male Mice Muscle Proteins - genetics Polymerase Chain Reaction Rats Rats, Inbred BN Rats, Sprague-Dawley RNA, Long Noncoding RNA, Untranslated Vertebrata
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