Resistance to ciprofloxacin appearing during therapy

The development of resistance to ciprofloxacin in nine clinical isolates of Pseudomonas aeruginosa was investigated. Isolates had increases in minimal inhibitory concentrations (MICs) from 0.25 to 16 μg/ml. The isolates also became resistant to ofloxacin and norfloxacin, but did not show increases i...

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Veröffentlicht in:	The American journal of medicine 1989-11, Vol.87 (5), p.S28-S31
Hauptverfasser:	Chin, Nai-Xun, Clynes, Neville, Neu, Harold C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial Outer Membrane Proteins - analysis Biological and medical sciences Ciprofloxacin - pharmacology Ciprofloxacin - therapeutic use Drug Resistance, Microbial Humans Medical sciences Microbial Sensitivity Tests Pharmacology. Drug treatments Pseudomonas aeruginosa - analysis Pseudomonas aeruginosa - drug effects
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